Q636K1 · Q636K1_BACCZ

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Allosterically activated by GTP. Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site12-15ATP (UniProtKB | ChEBI)
Binding site54UMP (UniProtKB | ChEBI)
Binding site55ATP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site74UMP (UniProtKB | ChEBI)
Binding site135-142UMP (UniProtKB | ChEBI)
Binding site163ATP (UniProtKB | ChEBI)
Binding site169ATP (UniProtKB | ChEBI)
Binding site172ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      smbA
    • Synonyms
      pyrH
    • Ordered locus names
      BCE33L3584

Organism names

Accessions

  • Primary accession
    Q636K1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain7-217Aspartate/glutamate/uridylate kinase
Region20-25Involved in allosteric activation by GTP

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    240
  • Mass (Da)
    25,870
  • Last updated
    2004-10-25 v1
  • Checksum
    38F617B1244D4B9D
MSKPKYNRVVLKLSGEALAGEQGFGINPAVIKSVAEQVKEIAELDVEVAVVVGGGNIWRGKIGSEMGMDRAGADYMGMLATVMNSLALQDSLENIGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYNADPSIDPTATKYETLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSVMEKGNIKRAVLGENIGTVVRGK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000001
EMBL· GenBank· DDBJ
AAU16682.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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