Q635G3 · BIOD_BACCZ

Function

function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site12-17ATP (UniProtKB | ChEBI)
Binding site16Mg2+ (UniProtKB | ChEBI)
Active site37
Binding site41substrate
Binding site51ATP (UniProtKB | ChEBI)
Binding site51Mg2+ (UniProtKB | ChEBI)
Binding site112Mg2+ (UniProtKB | ChEBI)
Binding site112-115ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functiondethiobiotin synthase activity
Molecular Functionmagnesium ion binding
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent dethiobiotin synthetase BioD
  • EC number
  • Alternative names
    • DTB synthetase
      (DTBS
      )
    • Dethiobiotin synthase

Gene names

    • Name
      bioD
    • Ordered locus names
      BCE33L3874

Organism names

Accessions

  • Primary accession
    Q635G3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003024771-242ATP-dependent dethiobiotin synthetase BioD

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the dethiobiotin synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    242
  • Mass (Da)
    26,265
  • Last updated
    2004-10-25 v1
  • Checksum
    6D5C2D1D1AAAF5C0
MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKPLQSGHVASNPEGDAARLKALSGVPTKEDEICPYSIEEPLAPRLAMKRAGRTVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKKEVLESAKEYIMISKLEECIRNESTVAHTSSN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000001
EMBL· GenBank· DDBJ
AAU16395.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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