Q63372 · NRX1A_RAT
- ProteinNeurexin-1
- GeneNrxn1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids1530 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Function is isoform-specific (By similarity).
Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission (By similarity).
Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca2+-triggered neurotransmitter release at synapses and at neuromuscular junctions (By similarity).
They play an important role in Ca2+-triggered exocytosis of secretory granules in pituitary gland (By similarity).
They may affect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery (By similarity).
Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels (By similarity).
Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2 (By similarity).
In vitro, triggers the de novo formation of presynaptic structures (PubMed:20064387, PubMed:20064388).
May be involved in specification of excitatory synapses (PubMed:20064387, PubMed:20064388).
Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (PubMed:20064387, PubMed:20064388).
Miscellaneous
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 345 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 362 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 430 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: M | ||||||
Binding site | 788 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 805 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 864 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 1199 | Ca2+ 3 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 1216 | Ca2+ 3 (UniProtKB | ChEBI) | ||||
Sequence: V | ||||||
Binding site | 1298 | Ca2+ 3 (UniProtKB | ChEBI) | ||||
Sequence: I | ||||||
Binding site | 1300 | Ca2+ 3 (UniProtKB | ChEBI) | ||||
Sequence: N |
GO annotations
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNeurexin-1
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionQ63372
Proteomes
Organism-specific databases
Subcellular Location
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 31-1454 | Extracellular | ||||
Sequence: LEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGSEVKLDEEPPNSGGGSPCEAGDEGDGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKEDNNVEGLAHLMMGDQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSRETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITHKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRVGGREPYPGSAEVIRESSSTT | ||||||
Transmembrane | 1455-1475 | Helical | ||||
Sequence: GMVVGIVAAAALCILILLYAM | ||||||
Topological domain | 1476-1530 | Cytoplasmic | ||||
Sequence: YKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, glycosylation, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-30 | |||||
Sequence: MGTALVQHGGCCLLCLSLLLLGCWAELGSG | ||||||
Chain | PRO_0000019491 | 31-1530 | Neurexin-1 | |||
Sequence: LEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGSEVKLDEEPPNSGGGSPCEAGDEGDGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKEDNNVEGLAHLMMGDQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSRETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITHKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRVGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV | ||||||
Glycosylation | 125 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 190 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 228↔243 | |||||
Sequence: CLNGGVCSVVDDQAVC | ||||||
Disulfide bond | 245↔255 | |||||
Sequence: CSRTGFRGKDC | ||||||
Disulfide bond | 460↔496 | |||||
Sequence: CLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKC | ||||||
Disulfide bond | 666↔695 | |||||
Sequence: CIRDLFIDGQSKDIRQMAEIQSTAGVKPSC | ||||||
Disulfide bond | 703↔714 | |||||
Sequence: CLSNPCKNNGMC | ||||||
Disulfide bond | 708↔723 | |||||
Sequence: CKNNGMCRDGWNRYVC | ||||||
Disulfide bond | 725↔735 | |||||
Sequence: CSGTGYLGRSC | ||||||
Glycosylation | 813 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 906↔914 | |||||
Sequence: CKNGDIDYC | ||||||
Disulfide bond | 1075↔1103 | |||||
Sequence: CLASVDLNGRLPDLISDALFCNGQIERGC | ||||||
Disulfide bond | 1110↔1121 | |||||
Sequence: CQEDSCSNQGVC | ||||||
Disulfide bond | 1115↔1130 | |||||
Sequence: CSNQGVCLQQWDGFSC | ||||||
Disulfide bond | 1132↔1142 | |||||
Sequence: CSMTSFSGPLC | ||||||
Glycosylation | 1246 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 1408 | O-linked (Xyl...) (heparan sulfate) serine | ||||
Sequence: S |
Post-translational modification
Keywords
- PTM
PTM databases
Expression
Tissue specificity
Interaction
Subunit
Also interacts (via laminin G-like domain 2 and/or laminin G-like domain 6) with NLGN2, NLGN3 and NLGN4L; interactions with NLGN1, NLGN2, NLGN3 and NLGN4L are calcium-dependent (PubMed:18093522).
Interacts (via cytoplasmic C-terminal region) with CASK (via the PDZ, SH3 and guanylate kinase-like domains) (PubMed:12040031, PubMed:8786425).
Interacts (via cytoplasmic C-terminus) with CASKIN1 and APBA1 (PubMed:12040031).
Interacts (via laminin G-like domain 2) with NXPH1 and NXPH3 (PubMed:9856994).
Alpha-type isoforms (neurexin-1-alpha) interact (via laminin G-like domain 2 and/or laminin G-like domain 6) with DAG1 (via alpha-dystroglycan chain) (PubMed:11470830).
Interacts with LRRTM1, LRRTM2, LRRTM3 and LRRTM4 (PubMed:20064387, PubMed:20064388).
Interacts with SYT13 and SYTL1 (By similarity).
Interacts with CBLN1, CBLN2 and, less avidly, with CBLN4 (By similarity).
Interacts with CLSTN3 (By similarity).
Alpha-type isoforms interact with alpha-latrotoxin from spider venom (PubMed:10197529, PubMed:1621094).
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 31-217 | Laminin G-like 1 | ||||
Sequence: LEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGSEVKLDEEPPNSGGGSPC | ||||||
Region | 196-219 | Disordered | ||||
Sequence: PVDGSEVKLDEEPPNSGGGSPCEA | ||||||
Domain | 213-255 | EGF-like 1 | ||||
Sequence: GGSPCEAGDEGDGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC | ||||||
Domain | 299-496 | Laminin G-like 2 | ||||
Sequence: IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKC | ||||||
Domain | 503-695 | Laminin G-like 3 | ||||
Sequence: DPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSC | ||||||
Domain | 699-736 | EGF-like 2 | ||||
Sequence: TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCE | ||||||
Domain | 741-914 | Laminin G-like 4 | ||||
Sequence: VLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYC | ||||||
Domain | 928-1103 | Laminin G-like 5 | ||||
Sequence: DPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGC | ||||||
Domain | 1106-1143 | EGF-like 3 | ||||
Sequence: PSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN | ||||||
Domain | 1149-1347 | Laminin G-like 6 | ||||
Sequence: YIFSKGGGQITHKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNV | ||||||
Region | 1412-1443 | Disordered | ||||
Sequence: PSDDEDIDPCEPSSGGLANPTRVGGREPYPGS | ||||||
Compositional bias | 1497-1513 | Polar residues | ||||
Sequence: NSAQSNGAVVKEKQPSS | ||||||
Region | 1497-1523 | Interaction with CASK | ||||
Sequence: NSAQSNGAVVKEKQPSSAKSANKNKKN | ||||||
Region | 1497-1530 | Disordered | ||||
Sequence: NSAQSNGAVVKEKQPSSAKSANKNKKNKDKEYYV | ||||||
Compositional bias | 1514-1530 | Basic and acidic residues | ||||
Sequence: AKSANKNKKNKDKEYYV |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoforms
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
This entry describes 17 isoforms produced by Alternative promoter usage & Alternative splicing. Two isoform types, alpha-type and beta-type are produced by alternative promoter usage. In addition there are at least five alternatively spliced sites, each of which may be spliced in up to seven different ways. Combinatorial splicing at each of these five sites may lead to the generation of at least 96 isoforms but for simplicity only individual splice events or observed combinations are explicitly described below. Beta-type isoforms share the possibility of alternative splicing at sites 4 and 5. Experimental confirmation may be lacking for some isoforms.
Q63372-2
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1a
- SynonymsAlpha-1A2A3A4A5A
- Length1,530
- Mass (Da)167,923
- Last updated2007-01-23 v3
- Checksum548109BAF05119FC
Q63372-1
- Name2a
- SynonymsAlpha-1B
- Differences from canonical
- 278-293: Missing
Q63372-3
- Name3a
- SynonymsAlpha-1C
- Differences from canonical
- 258-258: Missing
Q63372-4
- Name4a
- SynonymsAlpha-1D
- Differences from canonical
- 274-277: Missing
Q63372-5
- Name5a
- SynonymsAlpha-1E
Q63372-6
- Name6a
- SynonymsAlpha-1F
- Differences from canonical
- 264-273: Missing
Q63372-7
- Name7a
- SynonymsAlpha-1G
- Differences from canonical
- 258-277: Missing
Q63372-8
- Name8a
- SynonymsAlpha-2B
- Differences from canonical
- 403-409: Missing
Q63372-9
- Name9a
- SynonymsAlpha-2C
- Differences from canonical
- 395-409: Missing
Q63372-10
- Name10a
- SynonymsAlpha-3B
- Differences from canonical
- 806-815: DCIRINCNSS → G
Q63372-11
- Name11a
- SynonymsAlpha-4B
- Differences from canonical
- 1263-1292: Missing
Q63372-12
- Name12a
- SynonymsAlpha-5B
- Differences from canonical
- 1426-1427: Missing
Q63372-13
- Name13a
- SynonymsAlpha-1B2B
Q63373-1
The sequence of this isoform can be found in the external entry linked below. Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
View isoform- Name1b
- SynonymsBeta-4A5A
Q63373-2
The sequence of this isoform can be found in the external entry linked below. Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
View isoform- Name2b
- SynonymsBeta-4A5B
Q63373-3
The sequence of this isoform can be found in the external entry linked below. Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
View isoform- Name3b
- SynonymsBeta-4B5A
Q63373-4
The sequence of this isoform can be found in the external entry linked below. Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
View isoform- Name4b
- SynonymsBeta-4B5B
Computationally mapped potential isoform sequences
There are 8 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8I6GKK5 | A0A8I6GKK5_RAT | Nrxn1 | 1496 | ||
A0A8I6GKH3 | A0A8I6GKH3_RAT | Nrxn1 | 1504 | ||
A0A0U1RRR4 | A0A0U1RRR4_RAT | Nrxn1 | 1500 | ||
M0RBN6 | M0RBN6_RAT | Nrxn1 | 1484 | ||
A0A8I6A146 | A0A8I6A146_RAT | Nrxn1 | 1466 | ||
A0A8I5ZTY7 | A0A8I5ZTY7_RAT | Nrxn1 | 468 | ||
A0A8I5ZU71 | A0A8I5ZU71_RAT | Nrxn1 | 139 | ||
Q63373 | NRX1B_RAT | Nrxn1 | 468 |
Features
Showing features for alternative sequence, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_003486 | 258 | in isoform 3a and isoform 5a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_003487 | 258-277 | in isoform 7a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_022559 | 264-273 | in isoform 6a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_003488 | 274-277 | in isoform 4a and isoform 5a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_022560 | 278-293 | in isoform 2a and isoform 13a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_003489 | 395-409 | in isoform 9a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_003490 | 403-409 | in isoform 8a and isoform 13a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_003491 | 806-815 | in isoform 10a | |||
Sequence: DCIRINCNSS → G | ||||||
Alternative sequence | VSP_003492 | 1263-1292 | in isoform 11a | |||
Sequence: Missing | ||||||
Alternative sequence | VSP_003493 | 1426-1427 | in isoform 12a | |||
Sequence: Missing | ||||||
Compositional bias | 1497-1513 | Polar residues | ||||
Sequence: NSAQSNGAVVKEKQPSS | ||||||
Compositional bias | 1514-1530 | Basic and acidic residues | ||||
Sequence: AKSANKNKKNKDKEYYV |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M96374 EMBL· GenBank· DDBJ | AAA41704.1 EMBL· GenBank· DDBJ | mRNA |