Zic2 regulates the kinetics of neurulation.Nagai T., Aruga J., Minowa O., Sugimoto T., Ohno Y., Noda T., Mikoshiba K.View abstractCited forFUNCTION, DISRUPTION PHENOTYPECategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 97:1618-1623 (2000)Cited in1Mapped to16
Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins.Mizugishi K., Aruga J., Nakata K., Mikoshiba K.View abstractCited forFUNCTION, DNA-BINDINGCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 276:2180-2188 (2001)Cited in4Mapped to13
Zic2 controls cerebellar development in cooperation with Zic1.Aruga J., Inoue T., Hoshino J., Mikoshiba K.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Neurosci. 22:218-225 (2002)Cited in1Mapped to36
Zic2 patterns binocular vision by specifying the uncrossed retinal projection.Herrera E., Brown L., Aruga J., Rachel R.A., Dolen G., Mikoshiba K., Brown S., Mason C.A.View abstractCited forFUNCTION, DEVELOPMENTAL STAGECategoriesFunction, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 114:545-557 (2003)Cited in1Mapped to25
Myogenic repressor I-mfa interferes with the function of Zic family proteins.Mizugishi K., Hatayama M., Tohmonda T., Ogawa M., Inoue T., Mikoshiba K., Aruga J.View abstractCited forFUNCTION, INTERACTION WITH MDFICCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. Biophys. Res. Commun. 320:233-240 (2004)Cited in4Mapped to22
Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.Ishiguro A., Inoue T., Mikoshiba K., Aruga J.View abstractCited forFUNCTION, INTERACTION WITH MDFIC, SUBCELLULAR LOCATION, DNA-BINDINGCategoriesFunction, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. Biophys. Res. Commun. 324:302-307 (2004)Cited in4Mapped to25
Zic2 promotes axonal divergence at the optic chiasm midline by EphB1- dependent and -independent mechanisms.Garcia-Frigola C., Carreres M.I., Vegar C., Mason C., Herrera E.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDevelopment 135:1833-1841 (2008)Cited in1Mapped to6
Functional role of Zic2 phosphorylation in transcriptional regulation.Ishiguro A., Aruga J.View abstractCited forINTERACTION WITH DHX9, PHOSPHORYLATION AT SER-192 AND SER-200, DNA-BINDING, SUBCELLULAR LOCATION, MUTAGENESIS OF SER-192 AND SER-200CategoriesPTM / Processing, Function, Interaction, Phenotypes & Variants, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCFEBS Lett. 582:154-158 (2008)Cited in2Mapped to10
Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1.Lee R., Petros T.J., Mason C.A.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Neurosci. 28:5910-5919 (2008)Cited in2Mapped to4
Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets.Garcia-Frigola C., Herrera E.View abstractCited forFUNCTION, ASSOCIATION WITH DNA, DEVELOPMENTAL STAGECategoriesFunction, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 29:3170-3183 (2010)Cited in2Mapped to8
CXCL12 promotes the crossing of retinal ganglion cell axons at the optic chiasm.Le V.H., Orniacki C., Murcia-Belmonte V., Denti L., Schutz D., Stumm R., Ruhrberg C., Erskine L.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCDevelopment 151:dev202446-dev202446 (2024)Mapped to14
Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections.Fries M., Brown T.W., Jolicoeur C., Boulan B., Boudreau-Pinsonneault C., Javed A., Abram P., Cayouette M.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCCell Rep 42:112985-112985 (2023)Mapped to22
Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.Escuin S., Rose Raza-Knight S., Savery D., Gaston-Massuet C., Galea G.L., Greene N.D.E., Copp A.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 106679PubMedEurope PMCDis Model Mech 16:dmm049858-dmm049858 (2023)Mapped to99+
Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant.Min K.W., Kim N., Lee J.H., Sung Y., Kim M., Lee E.J., Kim J.M., Kim J.H., Lee J.[...], Kim J.W.View abstractCategoriesFunction, ExpressionSourceMGI: 106679PubMedEurope PMCExp Mol Med 55:385-400 (2023)Mapped to99+
CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism.Slavi N., Balasubramanian R., Lee M.A., Liapin M., Oaks-Leaf R., Peregrin J., Potenski A., Troy C.M., Ross M.E.[...], Mason C.A.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCNeuron 111:49-64.e5 (2023)Mapped to65
Ca<sup>2+</sup> homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.Yang K.Y., Zhao S., Feng H., Shen J., Chen Y., Wang S.T., Wang S.J., Zhang Y.X., Wang Y.[...], Tang T.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 106679PubMedEurope PMCCell Death Dis 13:674-674 (2022)Mapped to99+
Mesp1 controls the chromatin and enhancer landscapes essential for spatiotemporal patterning of early cardiovascular progenitors.Lin X., Swedlund B., Ton M.N., Ghazanfar S., Guibentif C., Paulissen C., Baudelet E., Plaindoux E., Achouri Y.[...], Blanpain C.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCNat Cell Biol 24:1114-1128 (2022)Mapped to23
Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia, and psychiatric behavior in mice.Chen X., Chen T., Dong C., Chen H., Dong X., Yang L., Hu L., Wang H., Wu B.[...], Zhou W.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCJ Genet Genomics 49:859-869 (2022)Mapped to55
SUMOylation Potentiates ZIC Protein Activity to Influence Murine Neural Crest Cell Specification.Bellchambers H.M., Barratt K.S., Diamand K.E.M., Arkell R.M.View abstractAnnotationSUMOylation Potentiates ZIC Protein Activity to Influence Murine Neural Crest Cell Specification.CategoryFunctionSourceGeneRif: 22772, MGI: 106679PubMedEurope PMCInt J Mol Sci 22:10437-10437 (2021)Mapped to13
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.Bedogni F., Hevner R.F.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCFront Mol Neurosci 14:686034-686034 (2021)Mapped to99+
Tlx3 Exerts Direct Control in Specifying Excitatory Over Inhibitory Neurons in the Dorsal Spinal Cord.Monteiro F.A., Miranda R.M., Samina M.C., Dias A.F., Raposo A.A.S.F., Oliveira P., Reguenga C., Castro D.S., Lima D.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCFront Cell Dev Biol 9:642697-642697 (2021)Mapped to51
Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.Li J., Sun L., Peng X.L., Yu X.M., Qi S.J., Lu Z.J., Han J.J., Shen Q.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCPLoS Genet 17:e1009355-e1009355 (2021)Mapped to90
Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala.Garcia-Calero E., Lopez-Gonzalez L., Martinez-de-la-Torre M., Fan C.M., Puelles L.View abstractCategoriesFunction, ExpressionSourceMGI: 106679PubMedEurope PMCBrain Struct Funct 226:519-562 (2021)Mapped to56
A Zic2-regulated switch in a noncanonical Wnt/betacatenin pathway is essential for the formation of bilateral circuits.Morenilla-Palao C., Lopez-Cascales M.T., Lopez-Atalaya J.P., Baeza D., Calvo-Diaz L., Barco A., Herrera E.View abstractCategoryFunctionSourceMGI: 106679PubMedEurope PMCSci Adv 6:eaaz8797-eaaz8797 (2020)Mapped to14
Genome-wide CRISPR screen identifies ZIC2 as an essential gene that controls the cell fate of early mesodermal precursors to human heart progenitors.Xu J., Zhou C., Foo K.S., Yang R., Xiao Y., Bylund K., Sahara M., Chien K.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 106679PubMedEurope PMCStem Cells 38:741-755 (2020)Mapped to3