Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.Thorvaldsen J.L., Duran K.L., Bartolomei M.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCGenes Dev 12:3693-3702 (1998)Mapped to7
Genomic imprinting and audiogenic seizures in mice.Banko M.L., Allen K.M., Dolina S., Neumann P.E., Seyfried T.N.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCBehav Genet 27:465-475 (1997)Mapped to2
Imprinting in clusters: lessons from Beckwith-Wiedemann syndrome.Reik W., Maher E.R.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCTrends Genet 13:330-334 (1997)Mapped to22
Parental-origin-specific epigenetic modification of the mouse H19 gene.Ferguson-Smith A.C., Sasaki H., Cattanach B.M., Surani M.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCNature 362:751-755 (1993)Mapped to2
Role for DNA methylation in genomic imprinting.Li E., Beard C., Jaenisch R.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCNature 366:362-365 (1993)Mapped to46
Regulation of genomic imprinting by gametic and embryonic processes.Chaillet J.R., Bader D.S., Leder P.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCGenes Dev 9:1177-1187 (1995)Mapped to2
Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.Bartolomei M.S., Webber A.L., Brunkow M.E., Tilghman S.M.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCGenes Dev 7:1663-1673 (1993)Mapped to2
Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype.Threadgill D.W., Dlugosz A.A., Hansen L.A., Tennenbaum T., Lichti U., Yee D., LaMantia C., Mourton T., Herrup K., Harris R.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCScience 269:230-234 (1995)Cited in1Mapped to19
Dysregulated <i>H19/Igf2</i> expression disrupts cardiac-placental axis during development of Silver-Russell syndrome-like mouse models.Chang S., Fulmer D., Hur S.K., Thorvaldsen J.L., Li L., Lan Y., Rhon-Calderon E.A., Leu N.A., Chen X.[...], Bartolomei M.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCElife 11:e78754-e78754 (2022)Mapped to23
Orientation of mouse H19 ICR affects imprinted H19 gene expression through promoter methylation-dependent and -independent mechanisms.Matsuzaki H., Miyajima Y., Fukamizu A., Tanimoto K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCCommun Biol 4:1410-1410 (2021)Mapped to7
The number of the CTCF binding sites of the H19/IGF2:IG-DMR correlates with DNA methylation and expression imprinting in a humanized mouse model.Freschi A., Del Prete R., Pignata L., Cecere F., Manfrevola F., Mattia M., Cobellis G., Sparago A., Bartolomei M.S.[...], Cerrato F.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCHum Mol Genet 30:1509-1520 (2021)Mapped to12
Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation.Wu H.Y., Cheng Y., Jin L.Y., Zhou Y., Pang H.Y., Zhu H., Yan C.C., Yan Y.S., Yu J.E.[...], Huang H.F.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCMol Cell Endocrinol 529:111264-111264 (2021)Mapped to7
The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma.Gamaev L., Mizrahi L., Friehmann T., Rosenberg N., Pappo O., Olam D., Zeira E., Bahar Halpern K., Caruso S.[...], Goldenberg D.S.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCOncogene 40:127-139 (2021)Mapped to5
Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2r<sup>I1565A</sup>) results in partial lethality, overgrowth and intestinal adenoma progression.Hughes J., Surakhy M., Can S., Ducker M., Davies N., Szele F., Buhnemann C., Carter E., Trikin R.[...], Hassan A.B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCSci Rep 9:11388-11388 (2019)Mapped to35
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development.Zhou J., Xu J., Zhang L., Liu S., Ma Y., Wen X., Hao J., Li Z., Ni Y.[...], Lan Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCCell Stem Cell 24:285-298.e5 (2019)Mapped to2
Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis.Yermalovich A.V., Osborne J.K., Sousa P., Han A., Kinney M.A., Chen M.J., Robinton D.A., Montie H., Pearson D.S.[...], Daley G.Q.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCNat Commun 10:168-168 (2019)Mapped to41
A Loss of Epigenetic Control Can Promote Cell Death through Reversing the Balance of Pathways in a Signaling Network.Vanaja K.G., Timp W., Feinberg A.P., Levchenko A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCMol Cell 72:60-70.e3 (2018)Mapped to6
H19 lncRNA Promotes Skeletal Muscle Insulin Sensitivity in Part by Targeting AMPK.Geng T., Liu Y., Xu Y., Jiang Y., Zhang N., Wang Z., Carmichael G.G., Taylor H.S., Li D., Huang Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCDiabetes 67:2183-2198 (2018)Cited in2Mapped to4
Imprinted gene dysregulation in a <i>Tet1</i> null mouse model is stochastic and variable in the germline and offspring.SanMiguel J.M., Abramowitz L.K., Bartolomei M.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCDevelopment 145:dev160622-dev160622 (2018)Mapped to50
Tissue-specific and mosaic imprinting defects underlie opposite congenital growth disorders in mice.Freschi A., Hur S.K., Valente F.M., Ideraabdullah F.Y., Sparago A., Gentile M.T., Oneglia A., Di Nucci D., Colucci-D'Amato L.[...], Cerrato F.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCPLoS Genet 14:e1007243-e1007243 (2018)Mapped to7
Loss of imprinting mutations define both distinct and overlapping roles for misexpression of IGF2 and of H19 lncRNA.Park K.S., Mitra A., Rahat B., Kim K., Pfeifer K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCNucleic Acids Res 45:12766-12779 (2017)Mapped to7
The Role of N-alpha-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting.Lee C.C., Peng S.H., Shen L., Lee C.F., Du T.H., Kang M.L., Xu G.L., Upadhyay A.K., Cheng X.[...], Juan L.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCMol Cell 68:89-103.e7 (2017)Mapped to29
TRIM28 Controls Genomic Imprinting through Distinct Mechanisms during and after Early Genome-wide Reprogramming.Alexander K.A., Wang X., Shibata M., Clark A.G., Garcia-Garcia M.J.View abstractCategoryPhenotypes & VariantsSourceMGI: 95891PubMedEurope PMCCell Rep 13:1194-1205 (2015)Mapped to26
ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis.Janssen L., Dupont L., Bekhouche M., Noel A., Leduc C., Voz M., Peers B., Cataldo D., Apte S.S.[...], Colige A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCAngiogenesis 19:53-65 (2016)Mapped to99+
De novo DNA methylation through the 5'-segment of the H19 ICR maintains its imprint during early embryogenesis.Matsuzaki H., Okamura E., Takahashi T., Ushiki A., Nakamura T., Nakano T., Hata K., Fukamizu A., Tanimoto K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95891PubMedEurope PMCDevelopment 142:3833-3844 (2015)Mapped to27