Q601Z4 · Q601Z4_MESH2
- ProteinHolliday junction resolvase RecU
- GenerecU
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids164 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.
Catalytic activity
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 60 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 62 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 75 | Mg2+ (UniProtKB | ChEBI) | |||
Site | 77 | Transition state stabilizer | |||
Binding site | 93 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | endonuclease activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleic acid binding | |
Biological Process | chromosome segregation | |
Biological Process | DNA recombination | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHolliday junction resolvase RecU
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mycoplasmoidales > Metamycoplasmataceae > Mesomycoplasma
Accessions
- Primary accessionQ601Z4
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length164
- Mass (Da)19,222
- Last updated2004-11-23 v1
- Checksum39572DEBCBD3FF74
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE017332 EMBL· GenBank· DDBJ | AAV27381.1 EMBL· GenBank· DDBJ | Genomic DNA |