Q5ZW91 · HIS4_LEGPH

Function

Catalytic activity

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.

Features

Showing features for active site.

123920406080100120140160180200220
TypeIDPosition(s)Description
Active site8Proton acceptor
Active site129Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
Biological ProcessL-histidine biosynthetic process
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
  • EC number
  • Alternative names
    • Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase

Gene names

    • Name
      hisA
    • Ordered locus names
      lpg1195

Organism names

Accessions

  • Primary accession
    Q5ZW91

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001420151-2391-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the HisA/HisF family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    239
  • Mass (Da)
    26,377
  • Last updated
    2004-11-23 v1
  • Checksum
    EC007CDC66444127
MLVIPAIDLQSGRCVRLKQGRFDQVTQFSVFPIERALHFAKLGAKRLHVVDLDGARSGKMQQLELICSMQKTGIPIQAGGGIRSIEQALECSNAGISQLVIGSLAITNPDLTIQIIEKIKPENIVLALDVRVDTKVPLLAINGWQNNSTSSLWEVVSYYENYGIKNILCTDIACDGMMNGPNFDLYQQAVEYFPQIAWQASGGVRHMQDITTLNSLGISAVILGLMLYQDHMNLEELLC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE017354
EMBL· GenBank· DDBJ
AAU27280.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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