Q5ZSC4 · Q5ZSC4_LEGPH
- ProteinPeptide deformylase
- Genedef
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids170 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
Catalytic activity
- H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]
Cofactor
Note: Binds 1 Fe2+ ion.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 91 | Fe cation (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 91 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 133 | Fe cation (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 133 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Active site | 134 | |||||
Sequence: E | ||||||
Binding site | 137 | Fe cation (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 137 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | peptide deformylase activity | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptide deformylase
- EC number
- Short namesPDF
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Legionellales > Legionellaceae > Legionella
Accessions
- Primary accessionQ5ZSC4
Proteomes
PTM/Processing
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length170
- Mass (Da)19,228
- Last updated2004-11-23 v1
- Checksum5DF901983C6E12B7
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE017354 EMBL· GenBank· DDBJ | AAU28653.1 EMBL· GenBank· DDBJ | Genomic DNA |