Q5ZLI9 · Q5ZLI9_CHICK
- Protein3-hydroxyisobutyrate dehydrogenase
- GeneHIBADH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids333 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+
Pathway
Amino-acid degradation; L-valine degradation.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 37-65 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 100-101 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 105 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 131 | NAD+ (UniProtKB | ChEBI) | |||
Active site | 206 | ||||
Binding site | 281 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-hydroxyisobutyrate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | valine catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-hydroxyisobutyrate dehydrogenase
- EC number
- Short namesHIBADH
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus
Accessions
- Primary accessionQ5ZLI9
Proteomes
Organism-specific databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 39-197 | 6-phosphogluconate dehydrogenase NADP-binding | |||
Domain | 200-326 | 3-hydroxyisobutyrate dehydrogenase-like NAD-binding | |||
Sequence similarities
Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length333
- Mass (Da)35,284
- Last updated2004-11-23 v1
- MD5 ChecksumC680011946E19D61CC5F2BF386930E47
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1D5PH80 | A0A1D5PH80_CHICK | HIBADH | 335 | ||
A0A8V0XAU1 | A0A8V0XAU1_CHICK | HIBADH | 308 | ||
A0A8V0X561 | A0A8V0X561_CHICK | HIBADH | 316 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ719745 EMBL· GenBank· DDBJ | CAG31404.1 EMBL· GenBank· DDBJ | mRNA |