Q5Y7D6 · Q5Y7D6_HUMAN
- ProteinHLA class II histocompatibility antigen DQ beta chain
- GeneHLA-DQB1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids261 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endosome membrane | |
Cellular Component | lysosomal membrane | |
Cellular Component | MHC class II protein complex | |
Biological Process | adaptive immune response | |
Biological Process | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ5Y7D6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Endosome membrane ; Single-pass type I membrane protein
Lysosome membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 231-251 | Helical | ||||
Sequence: MLSGVGGFVLGLIFLGLGLII |
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 522 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Genetic variation databases
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-30 | |||||
Sequence: MSWKKALRIPGDLRVATVTLMLAMLSSLLA | ||||||
Chain | PRO_5014587155 | 31-261 | ||||
Sequence: EGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLGLGLIIRQRSQKGLLH |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 129-217 | Ig-like | ||||
Sequence: PTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPIT |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length261
- Mass (Da)29,791
- Last updated2005-05-10 v1
- Checksum955BF0E22AA4BD79
Computationally mapped potential isoform sequences
There are 23 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P01920 | DQB1_HUMAN | HLA-DQB1 | 261 | ||
Q5Y7D3 | Q5Y7D3_HUMAN | HLA-DQB1 | 261 | ||
A2AAY8 | A2AAY8_HUMAN | HLA-DQB1 | 134 | ||
A2AAZ0 | A2AAZ0_HUMAN | HLA-DQB1 | 224 | ||
B4DJG1 | B4DJG1_HUMAN | HLA-DQB1 | 136 | ||
A0A0U5Q247 | A0A0U5Q247_HUMAN | HLA-DQB1 | 261 | ||
Q5SU54 | Q5SU54_HUMAN | HLA-DQB1 | 269 | ||
A0A140T9T0 | A0A140T9T0_HUMAN | HLA-DQB1 | 224 | ||
A0A140T9S8 | A0A140T9S8_HUMAN | HLA-DQB1 | 269 | ||
A0A140T9V6 | A0A140T9V6_HUMAN | HLA-DQB1 | 134 | ||
A0A140T9Y4 | A0A140T9Y4_HUMAN | HLA-DQB1 | 144 | ||
A0A140T9Z9 | A0A140T9Z9_HUMAN | HLA-DQB1 | 136 | ||
A0A140T9L5 | A0A140T9L5_HUMAN | HLA-DQB1 | 134 | ||
A0A140T9R6 | A0A140T9R6_HUMAN | HLA-DQB1 | 224 | ||
A0A140T9H9 | A0A140T9H9_HUMAN | HLA-DQB1 | 144 | ||
A0A140T8Z1 | A0A140T8Z1_HUMAN | HLA-DQB1 | 224 | ||
A0A140T8Z5 | A0A140T8Z5_HUMAN | HLA-DQB1 | 269 | ||
A0A140T981 | A0A140T981_HUMAN | HLA-DQB1 | 144 | ||
A0A140T911 | A0A140T911_HUMAN | HLA-DQB1 | 134 | ||
A0A0D5XQ77 | A0A0D5XQ77_HUMAN | HLA-DQB1 | 269 | ||
Q29967 | Q29967_HUMAN | HLA-DQB1 | 224 | ||
E9PIB1 | E9PIB1_HUMAN | HLA-DQB1 | 136 | ||
A0A140TA15 | A0A140TA15_HUMAN | HLA-DQB1 | 136 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL662789 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AY663395 EMBL· GenBank· DDBJ | AAU87980.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY663406 EMBL· GenBank· DDBJ | AAU88009.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY663411 EMBL· GenBank· DDBJ | AAU88024.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KF270555 EMBL· GenBank· DDBJ | AGW82949.2 EMBL· GenBank· DDBJ | Genomic DNA | ||
MF417566 EMBL· GenBank· DDBJ | AST16107.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KY856767 EMBL· GenBank· DDBJ | AVN68388.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KY856768 EMBL· GenBank· DDBJ | AVN68389.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK316333 EMBL· GenBank· DDBJ | BAH14704.1 EMBL· GenBank· DDBJ | mRNA | ||
AB774942 EMBL· GenBank· DDBJ | BAN59788.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB774978 EMBL· GenBank· DDBJ | BAN59824.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LC257874 EMBL· GenBank· DDBJ | BBD34192.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LC499658 EMBL· GenBank· DDBJ | BBN51266.1 EMBL· GenBank· DDBJ | mRNA | ||
LR777707 EMBL· GenBank· DDBJ | CAB0472741.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR777790 EMBL· GenBank· DDBJ | CAB0472824.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR777795 EMBL· GenBank· DDBJ | CAB0472829.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR812833 EMBL· GenBank· DDBJ | CAC8953929.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR812836 EMBL· GenBank· DDBJ | CAC8954013.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LN999672 EMBL· GenBank· DDBJ | CUX91065.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LN999677 EMBL· GenBank· DDBJ | CUX91070.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LN999709 EMBL· GenBank· DDBJ | CUX91102.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LN999710 EMBL· GenBank· DDBJ | CUX91103.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LN999767 EMBL· GenBank· DDBJ | CUX91160.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LN999771 EMBL· GenBank· DDBJ | CUX91164.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MN889869 EMBL· GenBank· DDBJ | QHR76763.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT066118 EMBL· GenBank· DDBJ | QIB02187.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MN461231 EMBL· GenBank· DDBJ | QJQ23414.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW605150 EMBL· GenBank· DDBJ | QSD59104.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MZ292453 EMBL· GenBank· DDBJ | QWE90336.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LT578429 EMBL· GenBank· DDBJ | SBO45770.1 EMBL· GenBank· DDBJ | Genomic DNA |