Q5Y7D6 · Q5Y7D6_HUMAN

  • Protein
    HLA class II histocompatibility antigen DQ beta chain
  • Gene
    HLA-DQB1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendosome membrane
Cellular Componentlysosomal membrane
Cellular ComponentMHC class II protein complex
Biological Processadaptive immune response
Biological Processantigen processing and presentation of peptide or polysaccharide antigen via MHC class II

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • HLA class II histocompatibility antigen DQ beta chain
    • HLA class II histocompatibility antigen, DQ beta 1 chain
    • MHC class II antigen
    • cDNA, FLJ79232, highly similar to HLA class II histocompatibility antigen, DQB1*0602 beta chain

Gene names

    • Name
      HLA-DQB1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DQ06NEW_Amelie_017418984
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q5Y7D6

Proteomes

Organism-specific databases

Subcellular Location

Endosome membrane
; Single-pass type I membrane protein
Lysosome membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane231-251Helical

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 522 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Genetic variation databases

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-30
ChainPRO_501458715531-261

Keywords

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain129-217Ig-like

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    261
  • Mass (Da)
    29,791
  • Last updated
    2005-05-10 v1
  • Checksum
    955BF0E22AA4BD79
MSWKKALRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLGLGLIIRQRSQKGLLH

Computationally mapped potential isoform sequences

There are 23 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P01920DQB1_HUMANHLA-DQB1261
Q5Y7D3Q5Y7D3_HUMANHLA-DQB1261
A2AAY8A2AAY8_HUMANHLA-DQB1134
A2AAZ0A2AAZ0_HUMANHLA-DQB1224
B4DJG1B4DJG1_HUMANHLA-DQB1136
A0A0U5Q247A0A0U5Q247_HUMANHLA-DQB1261
Q5SU54Q5SU54_HUMANHLA-DQB1269
A0A140T9T0A0A140T9T0_HUMANHLA-DQB1224
A0A140T9S8A0A140T9S8_HUMANHLA-DQB1269
A0A140T9V6A0A140T9V6_HUMANHLA-DQB1134
A0A140T9Y4A0A140T9Y4_HUMANHLA-DQB1144
A0A140T9Z9A0A140T9Z9_HUMANHLA-DQB1136
A0A140T9L5A0A140T9L5_HUMANHLA-DQB1134
A0A140T9R6A0A140T9R6_HUMANHLA-DQB1224
A0A140T9H9A0A140T9H9_HUMANHLA-DQB1144
A0A140T8Z1A0A140T8Z1_HUMANHLA-DQB1224
A0A140T8Z5A0A140T8Z5_HUMANHLA-DQB1269
A0A140T981A0A140T981_HUMANHLA-DQB1144
A0A140T911A0A140T911_HUMANHLA-DQB1134
A0A0D5XQ77A0A0D5XQ77_HUMANHLA-DQB1269
Q29967Q29967_HUMANHLA-DQB1224
E9PIB1E9PIB1_HUMANHLA-DQB1136
A0A140TA15A0A140TA15_HUMANHLA-DQB1136

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL662789
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AY663395
EMBL· GenBank· DDBJ
AAU87980.1
EMBL· GenBank· DDBJ
Genomic DNA
AY663406
EMBL· GenBank· DDBJ
AAU88009.1
EMBL· GenBank· DDBJ
Genomic DNA
AY663411
EMBL· GenBank· DDBJ
AAU88024.1
EMBL· GenBank· DDBJ
Genomic DNA
KF270555
EMBL· GenBank· DDBJ
AGW82949.2
EMBL· GenBank· DDBJ
Genomic DNA
MF417566
EMBL· GenBank· DDBJ
AST16107.1
EMBL· GenBank· DDBJ
Genomic DNA
KY856767
EMBL· GenBank· DDBJ
AVN68388.1
EMBL· GenBank· DDBJ
Genomic DNA
KY856768
EMBL· GenBank· DDBJ
AVN68389.1
EMBL· GenBank· DDBJ
Genomic DNA
AK316333
EMBL· GenBank· DDBJ
BAH14704.1
EMBL· GenBank· DDBJ
mRNA
AB774942
EMBL· GenBank· DDBJ
BAN59788.1
EMBL· GenBank· DDBJ
Genomic DNA
AB774978
EMBL· GenBank· DDBJ
BAN59824.1
EMBL· GenBank· DDBJ
Genomic DNA
LC257874
EMBL· GenBank· DDBJ
BBD34192.1
EMBL· GenBank· DDBJ
Genomic DNA
LC499658
EMBL· GenBank· DDBJ
BBN51266.1
EMBL· GenBank· DDBJ
mRNA
LR777707
EMBL· GenBank· DDBJ
CAB0472741.1
EMBL· GenBank· DDBJ
Genomic DNA
LR777790
EMBL· GenBank· DDBJ
CAB0472824.1
EMBL· GenBank· DDBJ
Genomic DNA
LR777795
EMBL· GenBank· DDBJ
CAB0472829.1
EMBL· GenBank· DDBJ
Genomic DNA
LR812833
EMBL· GenBank· DDBJ
CAC8953929.1
EMBL· GenBank· DDBJ
Genomic DNA
LR812836
EMBL· GenBank· DDBJ
CAC8954013.1
EMBL· GenBank· DDBJ
Genomic DNA
LN999672
EMBL· GenBank· DDBJ
CUX91065.1
EMBL· GenBank· DDBJ
Genomic DNA
LN999677
EMBL· GenBank· DDBJ
CUX91070.1
EMBL· GenBank· DDBJ
Genomic DNA
LN999709
EMBL· GenBank· DDBJ
CUX91102.1
EMBL· GenBank· DDBJ
Genomic DNA
LN999710
EMBL· GenBank· DDBJ
CUX91103.1
EMBL· GenBank· DDBJ
Genomic DNA
LN999767
EMBL· GenBank· DDBJ
CUX91160.1
EMBL· GenBank· DDBJ
Genomic DNA
LN999771
EMBL· GenBank· DDBJ
CUX91164.1
EMBL· GenBank· DDBJ
Genomic DNA
MN889869
EMBL· GenBank· DDBJ
QHR76763.1
EMBL· GenBank· DDBJ
Genomic DNA
MT066118
EMBL· GenBank· DDBJ
QIB02187.1
EMBL· GenBank· DDBJ
Genomic DNA
MN461231
EMBL· GenBank· DDBJ
QJQ23414.1
EMBL· GenBank· DDBJ
Genomic DNA
MW605150
EMBL· GenBank· DDBJ
QSD59104.1
EMBL· GenBank· DDBJ
Genomic DNA
MZ292453
EMBL· GenBank· DDBJ
QWE90336.1
EMBL· GenBank· DDBJ
Genomic DNA
LT578429
EMBL· GenBank· DDBJ
SBO45770.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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