Q5XKR9 · VCF2_HUMAN
- ProteinProtein VCF2
- GeneVCF2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids115 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein VCF2
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ5XKR9
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_055796 | 60 | in dbSNP:rs1047037 | |||
Sequence: S → G |
Variants
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The viewer provides 142 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000239034 | 1-115 | Protein VCF2 | |||
Sequence: MGGCPVRKRRRNGSKEGNHHSTQPKRNKRNPIFQDSQDTEFSWSDNERSSSRINIPERASGPEGNLNQIVTEPDANFPQFLHEGLSKPVYVINWFMSFGPEIKLNTSQQGRNQAV |
Proteomic databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q5XKR9-2 | APBB2 Q92870-2 | 3 | EBI-19946114, EBI-21535880 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-70 | Disordered | ||||
Sequence: MGGCPVRKRRRNGSKEGNHHSTQPKRNKRNPIFQDSQDTEFSWSDNERSSSRINIPERASGPEGNLNQIV | ||||||
Compositional bias | 27-56 | Polar residues | ||||
Sequence: NKRNPIFQDSQDTEFSWSDNERSSSRINIP |
Sequence similarities
Belongs to the VCF family.
Phylogenomic databases
Family and domain databases
Sequence & Isoforms
- Sequence statusComplete
This entry describes 6 isoforms produced by Alternative splicing.
Q5XKR9-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length115
- Mass (Da)13,109
- Last updated2004-11-23 v1
- Checksum44F92B3FDDC77CDB
Q5XKR9-2
- Name2
- Differences from canonical
- 40-40: E → EV
Q5XKR9-3
- Name3
Q5XKR9-4
- Name4
Q5XKR9-5
- Name5
- Differences from canonical
- 41-115: FSWSDNERSSSRINIPERASGPEGNLNQIVTEPDANFPQFLHEGLSKPVYVINWFMSFGPEIKLNTSQQGRNQAV → VAIFME
Q5XKR9-6
- Name6
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8I5KUH0 | A0A8I5KUH0_HUMAN | VCF2 | 115 |
Features
Showing features for alternative sequence, compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_044976 | 1-6 | in isoform 4 | |||
Sequence: MGGCPV → MTC | ||||||
Alternative sequence | VSP_046644 | 1-7 | in isoform 6 | |||
Sequence: MGGCPVR → MLVLWL | ||||||
Compositional bias | 27-56 | Polar residues | ||||
Sequence: NKRNPIFQDSQDTEFSWSDNERSSSRINIP | ||||||
Alternative sequence | VSP_019078 | 40 | in isoform 2 and isoform 3 | |||
Sequence: E → EV | ||||||
Alternative sequence | VSP_046645 | 41-115 | in isoform 5 | |||
Sequence: FSWSDNERSSSRINIPERASGPEGNLNQIVTEPDANFPQFLHEGLSKPVYVINWFMSFGPEIKLNTSQQGRNQAV → VAIFME | ||||||
Sequence conflict | 74 | in Ref. 1; BAG61768 | ||||
Sequence: D → V | ||||||
Alternative sequence | VSP_019079 | 85-115 | in isoform 3, isoform 4 and isoform 6 | |||
Sequence: LSKPVYVINWFMSFGPEIKLNTSQQGRNQAV → YVPCQGLYSHINQTLKEAHFNSLQQRGQAPT |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK299935 EMBL· GenBank· DDBJ | BAG61768.1 EMBL· GenBank· DDBJ | mRNA | ||
AL590240 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CH471154 EMBL· GenBank· DDBJ | EAW93218.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC000919 EMBL· GenBank· DDBJ | AAH00919.2 EMBL· GenBank· DDBJ | mRNA | ||
BC006406 EMBL· GenBank· DDBJ | AAH06406.2 EMBL· GenBank· DDBJ | mRNA | ||
BC017571 EMBL· GenBank· DDBJ | AAH17571.1 EMBL· GenBank· DDBJ | mRNA |