Q5XJV5 · Q5XJV5_MOUSE
- ProteinNuclear receptor coactivator 6
- GeneNcoa6
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2069 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | MLL3/4 complex | |
Molecular Function | enzyme binding | |
Molecular Function | nuclear receptor coactivator activity | |
Molecular Function | nuclear thyroid hormone receptor binding | |
Biological Process | DNA damage response | |
Biological Process | DNA-templated transcription initiation | |
Biological Process | myeloid cell differentiation | |
Biological Process | positive regulation of transcription by RNA polymerase II |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ5XJV5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 47-190 | Nuclear receptor coactivator 6 TRADD-N | ||||
Sequence: TIFVAFKGNIDDKDFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSVQIEGEGAINLALGQNRSQDVRMNGPVASGNSVRMEAGFPMASGPGLIRMTSPAAVMTPQGGNM | ||||||
Region | 181-253 | Disordered | ||||
Sequence: AVMTPQGGNMSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLPPAHHSMQPVPVNRQMN | ||||||
Compositional bias | 182-198 | Polar residues | ||||
Sequence: VMTPQGGNMSSSMMAPG | ||||||
Compositional bias | 223-237 | Polar residues | ||||
Sequence: GLHIQQQSHPSGSLP | ||||||
Compositional bias | 295-313 | Polar residues | ||||
Sequence: TRPLQQHQQQPQGIRPQFT | ||||||
Region | 295-550 | Disordered | ||||
Sequence: TRPLQQHQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTTNQGWKKAPLPSPMQAQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKGLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLSQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTAATPGNS | ||||||
Compositional bias | 331-353 | Polar residues | ||||
Sequence: ALQPPPAQGSLGTMTTNQGWKKA | ||||||
Compositional bias | 386-408 | Polar residues | ||||
Sequence: SQQASQAHTNFPQMSNPGQFTAP | ||||||
Compositional bias | 419-508 | Polar residues | ||||
Sequence: RVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLSQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQ | ||||||
Compositional bias | 529-550 | Polar residues | ||||
Sequence: QANPNFMQGQVPSTTAATPGNS | ||||||
Region | 562-583 | Disordered | ||||
Sequence: QHAGGQGAGPPQNQMQVSHGPP | ||||||
Region | 905-1281 | Disordered | ||||
Sequence: HFGVNNKQNNTNANKPKKKKPPRKKKNCHQDLNTPDNRPTGLEEVDQQSLPGEQGINLDTTGPKLPDFSNRPPGYPTQPVEQRPLPQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQMMMMLMMQQDPKSIRLPVSQNVHPPRGPLNPDSQRMPVQQSGNVPVMVGLQGPASVPPSPDKQRMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPEASGSEVPSVAGGPNNMPSHLVVSQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLN | ||||||
Compositional bias | 973-1028 | Pro residues | ||||
Sequence: SNRPPGYPTQPVEQRPLPQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQ | ||||||
Compositional bias | 1029-1043 | Polar residues | ||||
Sequence: SQQQQQQQQMMMMLM | ||||||
Compositional bias | 1101-1218 | Polar residues | ||||
Sequence: RMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPEASGSEVPSVAGGPNNMPSHLVVSQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPN | ||||||
Compositional bias | 1220-1234 | Pro residues | ||||
Sequence: ASPRPYYPQTPNNRP | ||||||
Region | 1315-1360 | Disordered | ||||
Sequence: VVNSGKQSNPGTTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKL | ||||||
Compositional bias | 1426-1449 | Polar residues | ||||
Sequence: NIPQDSDCQNAQGRKEQVNTELKV | ||||||
Region | 1426-1482 | Disordered | ||||
Sequence: NIPQDSDCQNAQGRKEQVNTELKVVPTQEAKMAVPEDQSKKDGQPLDPNKLPSVEEN | ||||||
Region | 1499-1595 | Disordered | ||||
Sequence: QLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLRKASVIPTLQDPPSKEPSTSLSSPHSSEPCSTLARSELSEVSSNTAPSIPPVMSRPVSSSSIST | ||||||
Compositional bias | 1542-1595 | Polar residues | ||||
Sequence: DPPSKEPSTSLSSPHSSEPCSTLARSELSEVSSNTAPSIPPVMSRPVSSSSIST | ||||||
Compositional bias | 1771-1818 | Polar residues | ||||
Sequence: LNPDEASPQTNTSADQSTLPPSQPTTVVSPLLTNSPGSSANRRSPVSS | ||||||
Region | 1771-1824 | Disordered | ||||
Sequence: LNPDEASPQTNTSADQSTLPPSQPTTVVSPLLTNSPGSSANRRSPVSSSKGKGK | ||||||
Region | 1842-1913 | Disordered | ||||
Sequence: GSLEKGEEQYGADGETEGPGLEITTPGLMGTEQCSTELDSKTPTPSAPTLLKMTSSPMGPSSTSTGPILPGG | ||||||
Compositional bias | 1869-1911 | Polar residues | ||||
Sequence: LMGTEQCSTELDSKTPTPSAPTLLKMTSSPMGPSSTSTGPILP | ||||||
Region | 1933-2069 | Disordered | ||||
Sequence: STAPTTKGNHGGVTSEPLAGGLVEEKVGSHPELLPSIAPSQNLAPKETPATALQGSVARPELEANAAIASGQSCEPKEIVEKSKTLTSRRNSRTEEPTMASESVENGHRKRSSRPASASSSTKDITGAVQSKRRKSK | ||||||
Compositional bias | 2009-2023 | Basic and acidic residues | ||||
Sequence: KEIVEKSKTLTSRRN | ||||||
Compositional bias | 2045-2059 | Polar residues | ||||
Sequence: SRPASASSSTKDITG |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,069
- Mass (Da)219,958
- Last updated2004-11-23 v1
- Checksum018B0C0F6886A200
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 182-198 | Polar residues | ||||
Sequence: VMTPQGGNMSSSMMAPG | ||||||
Compositional bias | 223-237 | Polar residues | ||||
Sequence: GLHIQQQSHPSGSLP | ||||||
Compositional bias | 295-313 | Polar residues | ||||
Sequence: TRPLQQHQQQPQGIRPQFT | ||||||
Compositional bias | 331-353 | Polar residues | ||||
Sequence: ALQPPPAQGSLGTMTTNQGWKKA | ||||||
Compositional bias | 386-408 | Polar residues | ||||
Sequence: SQQASQAHTNFPQMSNPGQFTAP | ||||||
Compositional bias | 419-508 | Polar residues | ||||
Sequence: RVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLSQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQ | ||||||
Compositional bias | 529-550 | Polar residues | ||||
Sequence: QANPNFMQGQVPSTTAATPGNS | ||||||
Compositional bias | 973-1028 | Pro residues | ||||
Sequence: SNRPPGYPTQPVEQRPLPQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQ | ||||||
Compositional bias | 1029-1043 | Polar residues | ||||
Sequence: SQQQQQQQQMMMMLM | ||||||
Compositional bias | 1101-1218 | Polar residues | ||||
Sequence: RMPMSVNTPMGSNSRKMVYQENPQNSSSSPLGEMSSLPEASGSEVPSVAGGPNNMPSHLVVSQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPN | ||||||
Compositional bias | 1220-1234 | Pro residues | ||||
Sequence: ASPRPYYPQTPNNRP | ||||||
Compositional bias | 1426-1449 | Polar residues | ||||
Sequence: NIPQDSDCQNAQGRKEQVNTELKV | ||||||
Compositional bias | 1542-1595 | Polar residues | ||||
Sequence: DPPSKEPSTSLSSPHSSEPCSTLARSELSEVSSNTAPSIPPVMSRPVSSSSIST | ||||||
Compositional bias | 1771-1818 | Polar residues | ||||
Sequence: LNPDEASPQTNTSADQSTLPPSQPTTVVSPLLTNSPGSSANRRSPVSS | ||||||
Compositional bias | 1869-1911 | Polar residues | ||||
Sequence: LMGTEQCSTELDSKTPTPSAPTLLKMTSSPMGPSSTSTGPILP | ||||||
Compositional bias | 2009-2023 | Basic and acidic residues | ||||
Sequence: KEIVEKSKTLTSRRN | ||||||
Compositional bias | 2045-2059 | Polar residues | ||||
Sequence: SRPASASSSTKDITG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC083187 EMBL· GenBank· DDBJ | AAH83187.1 EMBL· GenBank· DDBJ | mRNA |