Q5XJA4 · Q5XJA4_DANRE

Function

function

The glycine cleavage system catalyzes the degradation of glycine.

Catalytic activity

Features

Showing features for binding site.

140950100150200250300350400
TypeIDPosition(s)Description
Binding site239substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentglycine cleavage complex
Cellular Componentmitochondrion
Molecular Functionaminomethyltransferase activity
Molecular Functionmethyltransferase activity
Molecular Functiontransaminase activity
Biological Processglycine catabolic process
Biological Processmethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aminomethyltransferase
  • EC number
  • Alternative names
    • Glycine cleavage system T protein

Gene names

    • Name
      amt
    • Synonyms
      fc31f04
      , wu:fc31f04
      , wu:fd44b12
      , wu:fd54h12
      , zgc:103483
      , zgc:109741

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q5XJA4

Proteomes

    • Identifier
    • Component
      Alternate scaffold 8, Chromosome 8

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

The glycine cleavage system is composed of four proteins: P, T, L and H.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain45-298Aminomethyltransferase folate-binding
Domain325-402Glycine cleavage T-protein C-terminal barrel

Sequence similarities

Belongs to the GcvT family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    409
  • Mass (Da)
    44,742
  • Last updated
    2004-11-23 v1
  • Checksum
    94E9D4DC9CBF9E99
MLARAFANGLCKRLSRESTRAVGLGATGRQDRQASTEVTLRKTPLYDFHRAHGGKMVEFAGWSMPVQYKDSHITSHMHTRQHCSIFDVSHMLQTKVYGKDRVKFIESLIVGDIAELKDNQGTLSLFTNSKGGIMDDLIVTKTDQDYLYVVSNAGCADKDSAHMQARLQEFKSAGHDVDLEFMEESLIALQGPSMARVLQKGVGDDLKKLTFMTSVLTPVFGIQGCRVTRCGYTGEDGVEISVPSKDVVLLTEKLLADSEVKLAGLGARDSLRLEAGLCLYGNDIDETTTPVEATLVWTIGKRRRQARDFPGADIIVPQIKAKTPRKRVGLISTGPPVRQHTPILSSDGRVIGEVTSGCPSPCLKQNVAMGYVETAFSKAGTSIQVEVRKKAVPAVVSKMPFVPTKYYMG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC083400
EMBL· GenBank· DDBJ
AAH83400.1
EMBL· GenBank· DDBJ
mRNA
BC164008
EMBL· GenBank· DDBJ
AAI64008.1
EMBL· GenBank· DDBJ
mRNA
DQ104411
EMBL· GenBank· DDBJ
AAZ08415.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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