Q5XHY4 · NAR5_RAT
- ProteinEcto-ADP-ribosyltransferase 5
- GeneArt5
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids308 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- L-arginyl-[protein] + NAD+ = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 100 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Active site | 161 | |||||
Sequence: R | ||||||
Binding site | 161 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 181 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Active site | 184 | |||||
Sequence: S | ||||||
Binding site | 215 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Active site | 222 | |||||
Sequence: E |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | membrane | |
Molecular Function | NAD+-protein poly-ADP-ribosyltransferase activity | |
Molecular Function | NAD+-protein-arginine ADP-ribosyltransferase activity | |
Molecular Function | nucleotidyltransferase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEcto-ADP-ribosyltransferase 5
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionQ5XHY4
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for signal, chain, disulfide bond, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-23 | |||||
Sequence: MILEDLLMVLSCLALHILWKVQA | ||||||
Chain | PRO_0000379472 | 24-308 | Ecto-ADP-ribosyltransferase 5 | |||
Sequence: VPILPLSLVPDTFDDAYVGCSEEMEEKAGLLLKEEMARHALLRESWEAAQEAWAHGRHKLTLPPGFKAQHGVAVMVYTNSSNTLYWELNQAVRTGGRSRELYMRHFPFKALHFYLTRALQLLRGTGGCSREAGEVVFRGVSSLHFEPKRLGDSVRLGQFASSSVDERVARRFGNATFFNLRTCFGAPIQALSVFPEEREVLIPPHEVFLVTGFSQDGAQSIVTLWSYNQTCSHFNCAYLGGEKRRGCVSSRAGQPESFSTEALALQSGKTLLLAPGELQLSRAGP | ||||||
Disulfide bond | 43↔259 | |||||
Sequence: CSEEMEEKAGLLLKEEMARHALLRESWEAAQEAWAHGRHKLTLPPGFKAQHGVAVMVYTNSSNTLYWELNQAVRTGGRSRELYMRHFPFKALHFYLTRALQLLRGTGGCSREAGEVVFRGVSSLHFEPKRLGDSVRLGQFASSSVDERVARRFGNATFFNLRTCFGAPIQALSVFPEEREVLIPPHEVFLVTGFSQDGAQSIVTLWSYNQTCSHFNC | ||||||
Glycosylation | 102 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 197 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 251 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 63-253 | TR mART core | ||||
Sequence: ALLRESWEAAQEAWAHGRHKLTLPPGFKAQHGVAVMVYTNSSNTLYWELNQAVRTGGRSRELYMRHFPFKALHFYLTRALQLLRGTGGCSREAGEVVFRGVSSLHFEPKRLGDSVRLGQFASSSVDERVARRFGNATFFNLRTCFGAPIQALSVFPEEREVLIPPHEVFLVTGFSQDGAQSIVTLWSYNQT |
Sequence similarities
Belongs to the Arg-specific ADP-ribosyltransferase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length308
- Mass (Da)34,201
- Last updated2004-11-23 v1
- Checksum45B0063435437D2F
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8I6ATX6 | A0A8I6ATX6_RAT | Art5 | 211 | ||
A0A8L2QQ22 | A0A8L2QQ22_RAT | Art5 | 309 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC083915 EMBL· GenBank· DDBJ | AAH83915.1 EMBL· GenBank· DDBJ | mRNA |