Q5WNX0 · BCRA_ENTFL

Function

function

Essential for high-level bacitracin resistance (PubMed:15388429).
Part of the ABC transporter complex BcrAB. Probably responsible for energy coupling to the transport system (Probable)

Features

Showing features for binding site.

130820406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site40-47ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Biological Processresponse to antibiotic

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Bacitracin transport ATP-binding protein BcrA

Gene names

    • Name
      bcrA

Encoded on

  • Plasmid pJM01

Organism names

Accessions

  • Primary accession
    Q5WNX0

Phenotypes & Variants

Disruption phenotype

Disruption mutant is sensitive to bacitracin.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004473661-308Bacitracin transport ATP-binding protein BcrA

Expression

Induction

Transcription is activated by the regulatory protein BcrR in the presence of bacitracin.

Interaction

Subunit

The complex is probably composed of two ATP-binding proteins (BcrA) and two transmembrane proteins (BcrB).

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-236ABC transporter

Sequence similarities

Belongs to the ABC transporter superfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    308
  • Mass (Da)
    34,291
  • Last updated
    2004-11-23 v1
  • Checksum
    ED194215F70E1FC6
MMIMEYVIETENLTKQYGETTVVNKINLHVPKGKIYGLLGRNGAGKTTAMKMMLQLAFPTDGTVRLFGTNYKENIHTLYSKVGSIIETPGFYSNLTGYENLQILAKLRGGVSKSGVEKALEVVGLHKEKRKVFSDYSLGMKQRLGIAAAIMHEPELLILDEPINGLDPIGISEIRSFLSKLSHENGTTIFISSHVLSEIEQIADVIGVMHEGHLVEEVNISELHKRNRKYTEFDVSDGKIAAKILESSYHMTDFTVQDGTIRIYDFSQSVGEINREFARNGLLITRINDSEENLEDYFSKLIGGGGIA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY496968
EMBL· GenBank· DDBJ
AAS78451.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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