Q5WGP6 · Q5WGP6_SHOC1

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

149550100150200250300350400450
TypeIDPosition(s)Description
Binding site15-22NADP+ (UniProtKB | ChEBI)
Binding site49NADP+ (UniProtKB | ChEBI)
Binding site90-91NADP+ (UniProtKB | ChEBI)
Binding site153NADP+ (UniProtKB | ChEBI)
Binding site183substrate
Binding site187substrate
Binding site221substrate
Binding site240substrate
Active site245Proton acceptor
Binding site345substrate
Binding site350substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • Ordered locus names
      ABC1924

Organism names

Accessions

  • Primary accession
    Q5WGP6

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain12-192Glucose-6-phosphate dehydrogenase NAD-binding
Domain195-490Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    495
  • Mass (Da)
    56,528
  • Last updated
    2004-11-23 v1
  • Checksum
    E5FDBB0316AC2F7B
MNQIEQAEAVFVIFGSTGDLAKRKLFPSIYNLYRKGNLNEHFAVVGLGRREWDDEKLRTVVMESIQEELGEQRPEVTESFLKHFSYLSFDVTNKDSYSELNDKLHILDETFQIPGNRIFYMAMAPEFFGQIAQSIHNEGLKDTQGWTRLVIEKPFGTDLQSAIRLNDEIRQAFSEDEIYRIDHYLGKEMVQNIQVIRFANAIFGSLWNNRHIANIQVTSSEQLGVEGRGGYYEKSGALRDMVQNHMLQMVSLLAMDVPLRLSTDDIRSEKIKVLRALRPIVGESIKENVVRGQYGRGEINGQEVIGYLEEENVSDSSKTETYVAAKLMIDNHVWAGVPFYIRTGKRMAVKSTKIVVEFKELPLNLYSKENKQTGPNLLIIHIQPDEGMTIVLNGKKIGSADTTPVHLQYRHDSEDRFNTPEAYERLLFDCMMGDATNFAHWDEVSLSWSLVDAISKAWSESGEKLPTYRAGSMGPKEADELLEADGFSWWPVEEM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP006627
EMBL· GenBank· DDBJ
BAD64459.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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