Q5W0A0 · ERI6B_HUMAN
- ProteinGlutamate-rich protein 6B
- GeneERICH6B
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids696 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamate-rich protein 6B
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ5W0A0
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_039969 | 63 | in dbSNP:rs12020217 | |||
Sequence: E → D | ||||||
Natural variant | VAR_039970 | 99 | in dbSNP:rs12020731 | |||
Sequence: E → G | ||||||
Natural variant | VAR_039971 | 174 | in dbSNP:rs17066954 | |||
Sequence: S → T | ||||||
Natural variant | VAR_039972 | 178 | in dbSNP:rs3014939 | |||
Sequence: E → K | ||||||
Natural variant | VAR_039973 | 303 | in dbSNP:rs11618506 | |||
Sequence: L → P | ||||||
Natural variant | VAR_039974 | 427 | in dbSNP:rs749071 | |||
Sequence: T → I | ||||||
Natural variant | VAR_039975 | 439 | in dbSNP:rs12429125 | |||
Sequence: P → R | ||||||
Natural variant | VAR_039976 | 453 | in dbSNP:rs17066902 | |||
Sequence: H → R | ||||||
Natural variant | VAR_039977 | 565 | in dbSNP:rs7327901 | |||
Sequence: R → C | ||||||
Natural variant | VAR_039978 | 653 | in dbSNP:rs1536207 | |||
Sequence: V → F |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 741 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000326050 | 1-696 | Glutamate-rich protein 6B | |||
Sequence: MSAENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENRWKLVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRVVHHRKKLERDKEWIQKKTVVHQGDGKLILYPNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILEDSLEGRIRALINNSGNATFYDENSDIWLNLSSNLGYYFPKDKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQIRSQDKIIFCFTYEQKQICLNLGTRYKFVIPEVLSEMKKKTILEAEPGPTAQKIRVLLGKMNRLLNYATTPDLENFIEAVSISLMDNKYLKKMLSKLWF |
Proteomic databases
PTM databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-105 | Disordered | ||||
Sequence: MSAENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAGYLE | ||||||
Compositional bias | 33-47 | Acidic residues | ||||
Sequence: DTEVELDEESLQDES | ||||||
Compositional bias | 57-73 | Acidic residues | ||||
Sequence: EDKEYLEEEEDLEEEEY | ||||||
Compositional bias | 74-98 | Basic and acidic residues | ||||
Sequence: LGKEEYLKEEEYLGKEEHLEEEEYL |
Sequence similarities
Belongs to the ERICH6 family.
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q5W0A0-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length696
- Mass (Da)81,686
- Last updated2004-12-07 v1
- ChecksumE82E8019FB58C9A9
Q5W0A0-2
- Name2
- Differences from canonical
- 134-139: Missing
Features
Showing features for compositional bias, sequence conflict, alternative sequence.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 33-47 | Acidic residues | ||||
Sequence: DTEVELDEESLQDES | ||||||
Compositional bias | 57-73 | Acidic residues | ||||
Sequence: EDKEYLEEEEDLEEEEY | ||||||
Compositional bias | 74-98 | Basic and acidic residues | ||||
Sequence: LGKEEYLKEEEYLGKEEHLEEEEYL | ||||||
Sequence conflict | 101 | in Ref. 1; BAB71393 | ||||
Sequence: A → V | ||||||
Alternative sequence | VSP_032523 | 134-139 | in isoform 2 | |||
Sequence: Missing |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK057244 EMBL· GenBank· DDBJ | BAB71393.1 EMBL· GenBank· DDBJ | mRNA | ||
AL139326 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |