Q5U676 · Q5U676_HUMAN

  • Protein
    Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
  • Gene
    B3GAT3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Protein modification; protein glycosylation.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site88-90UDP-alpha-D-glucuronate (UniProtKB | ChEBI)
Binding site119UDP-alpha-D-glucuronate (UniProtKB | ChEBI)
Binding site162UDP-alpha-D-glucuronate (UniProtKB | ChEBI)
Binding site167UDP-alpha-D-glucuronate (UniProtKB | ChEBI)
Binding site200-202UDP-alpha-D-glucuronate (UniProtKB | ChEBI)
Binding site202Mn2+ (UniProtKB | ChEBI)
Site233Interaction with galactose moiety of substrate glycoprotein
Active site287Proton donor/acceptor
Binding site314-316UDP-alpha-D-glucuronate (UniProtKB | ChEBI)
Site324Interaction with galactose moiety of substrate glycoprotein

GO annotations

AspectTerm
Cellular ComponentGolgi membrane
Molecular Functiongalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
Molecular Functionmetal ion binding
Biological Processprotein glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
  • EC number

Gene names

    • Name
      B3GAT3

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q5U676

Subcellular Location

Golgi apparatus membrane
; Single-pass type II membrane protein

Keywords

Disease & Variants

Organism-specific databases

PTM/Processing

Features

Showing features for disulfide bond, glycosylation.

TypeIDPosition(s)Description
Disulfide bond39Interchain
Glycosylation306N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region318-341Disordered

Sequence similarities

Belongs to the glycosyltransferase 43 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    341
  • Mass (Da)
    37,828
  • Last updated
    2004-12-07 v1
  • Checksum
    130B8EDDBB67DE88
LLGRGRRRGHEAEAEERVSRLLPGVDRRPPLRAGQPCDCLPPLRAAAEQLRQKDLRISQLQAELRRPPPAPAQPPEPEALPTIYVVTPTYARLVQKAELVRLSQTLSLVPRLHWLLVEDAEGPTPLVSGLLAASGLLFTHLVVLTPKAQRLREGEPGWVHPRGVEQRNKALDWLRGRGGAVGGEKDPPPPGTQGVVYFADDDNTYSRELFEEMRWTRGVSVWPVGLVGGLRFEGPQVQDGRVVGFHTAWEPSRPFPVDMAGFAVALPLLLDKPNAQFDSTAPRGHLESSLLSHLVDPKDLEPRAANCTRVLVWHTRTEKPKMKQEEQLQRQGRGSDPAIEV

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC019832
EMBL· GenBank· DDBJ
AAH19832.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp