Q5U3V6 · Q5U3V6_DANRE

Function

function

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleoplasm
Molecular FunctionmRNA binding
Molecular FunctionN6-methyladenosine-containing RNA reader activity
Biological ProcessmRNA splicing, via spliceosome
Biological Processregulation of alternative mRNA splicing, via spliceosome
Biological Processregulation of mRNA stability

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    YTH domain-containing family protein

Gene names

    • Name
      ythdc1
    • Synonyms
      zgc:101592

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q5U3V6

Proteomes

    • Identifier
    • Component
      Alternate scaffold 5, Chromosome 5

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Region1-281Disordered
Compositional bias33-63Basic and acidic residues
Compositional bias70-87Polar residues
Compositional bias88-108Basic and acidic residues
Compositional bias126-169Basic and acidic residues
Compositional bias187-232Acidic residues
Compositional bias246-266Polar residues
Compositional bias267-281Basic and acidic residues
Domain299-436YTH
Region453-481Disordered
Compositional bias464-481Basic and acidic residues
Region494-519Disordered
Compositional bias561-582Pro residues
Region561-589Disordered
Region623-679Disordered
Compositional bias626-679Basic and acidic residues

Sequence similarities

Belongs to the YTHDF family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    679
  • Mass (Da)
    78,660
  • Last updated
    2004-12-07 v1
  • Checksum
    FD430DB297E550D1
MSVDRRDEKDGELNVLEDILTDAPDQDDELYNPESEHDVNEKKGSKRKHDRGDAQDAKRLRASGHNTRQPMKRAAPSSGSNGKKTSNPRGRHAPEDLYDDRKNHSGRGGASRADLSKGYGEKGLSSSRDSQRRIKPLMPELTEKMRRTSEESAGRASRSSREEEAHSEEYATGSSVASSEGNCSDVEEEGAMPEEGEEKEGEEEEEEEEEGDDDDDEEEEYVLEEEDAREGNEQNDYDTRSEASDSRSESVSFSDGESVHSASGSDASGSEKKHEKLSSSVRDVRKDRINKLKHILREARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNAAFRAARSVVLIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMNAKMLGGVFKIDWICRRELPFTKTAHLANPWNEHKPVKIGRDGQEIEPECGTELCMLFPHDESIDLYQVIHKMRHKRRMHSEPRSRGRLPHREPVPRDMGRRRPEEYDMHNRKRPRIDYTPEFPQRPGFMQDPRNPPVDRRFSGVRRDVFLNGSYNDYMREFHHNIGPPPPWQGMAPYPGMEHPPQHPYYQHHPPPPQAHPPYSGHHPMPHDARFREKRVVRSFASSLHDYDMRVDDFLRRTQAVVSGRRSRPRERDRQRERDRPRDGRRDRERERGRERDRERERIRDREREKERGRYRR

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M3B309A0A8M3B309_DANREythdc1553
A0A8M9QDV6A0A8M9QDV6_DANREythdc1678

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Compositional bias33-63Basic and acidic residues
Compositional bias70-87Polar residues
Compositional bias88-108Basic and acidic residues
Compositional bias126-169Basic and acidic residues
Compositional bias187-232Acidic residues
Compositional bias246-266Polar residues
Compositional bias267-281Basic and acidic residues
Compositional bias464-481Basic and acidic residues
Compositional bias561-582Pro residues
Compositional bias626-679Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC085378
EMBL· GenBank· DDBJ
AAH85378.1
EMBL· GenBank· DDBJ
mRNA
BC165861
EMBL· GenBank· DDBJ
AAI65861.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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