Q5TZ66 · SN25A_DANRE

Function

function

May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Cellular Componentneuron projection
Cellular Componentplasma membrane
Cellular Componentpresynapse
Cellular ComponentSNARE complex
Cellular Componentsynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
Molecular FunctionSNAP receptor activity
Molecular Functionsyntaxin-1 binding
Molecular Functionvoltage-gated potassium channel activity
Biological Processexocytosis
Biological Processlocomotory behavior
Biological Processmitotic cytokinesis
Biological Processsynaptic vesicle fusion to presynaptic active zone membrane
Biological Processsynaptic vesicle priming

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Synaptosomal-associated protein 25-A
  • Short names
    SNAP-25A
  • Alternative names
    • Synaptosome-associated protein 25.1
      (SNAP-25.1
      )

Gene names

    • Name
      snap25a
    • Synonyms
      Snap
      , snap25.1
    • ORF names
      si:dkeyp-8f4.6

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q5TZ66
  • Secondary accessions
    • O93578
    • Q5TZ65
    • Q6P3L7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003555741-204Synaptosomal-associated protein 25-A

Proteomic databases

Expression

Tissue specificity

Expressed in several regions throughout the adult brain, including the mesencephalon.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-25Disordered
Domain19-81t-SNARE coiled-coil homology 1
Domain138-200t-SNARE coiled-coil homology 2

Sequence similarities

Belongs to the SNAP-25 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing. Isoforms differ by the usage of two alternative homologous exons which code for positions 55 to 94 and differ only in 11 positions out of 40.

Q5TZ66-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    204
  • Mass (Da)
    22,857
  • Last updated
    2004-12-07 v1
  • Checksum
    B53CF5F3D1C69EA5
MAEDSDMRNELADMQQRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKDAEKNLNDLGKFCGLCSCPCNKMKSGASKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTDDARENEMDENLEQVGGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG

Q5TZ66-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 58-89: ERIEEGMDQINKDMKDAEKNLNDLGKFCGLCS → DRVEDGMNHINQDMKEAEKNLKDLGKCCGLFI

Features

Showing features for alternative sequence, sequence conflict.

TypeIDPosition(s)Description
Alternative sequenceVSP_05297458-89in isoform 2
Sequence conflict190in Ref. 2; AAH63942

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX465184
EMBL· GenBank· DDBJ
CAH69031.1
EMBL· GenBank· DDBJ
Genomic DNA
BX470246
EMBL· GenBank· DDBJ
CAH69031.1
EMBL· GenBank· DDBJ
Genomic DNA
BX465184
EMBL· GenBank· DDBJ
CAH69032.1
EMBL· GenBank· DDBJ
Genomic DNA
BX470246
EMBL· GenBank· DDBJ
CAH69032.1
EMBL· GenBank· DDBJ
Genomic DNA
BX470246
EMBL· GenBank· DDBJ
CAI21359.1
EMBL· GenBank· DDBJ
Genomic DNA
BX465184
EMBL· GenBank· DDBJ
CAI21359.1
EMBL· GenBank· DDBJ
Genomic DNA
BX470246
EMBL· GenBank· DDBJ
CAI21360.1
EMBL· GenBank· DDBJ
Genomic DNA
BX465184
EMBL· GenBank· DDBJ
CAI21360.1
EMBL· GenBank· DDBJ
Genomic DNA
BC063942
EMBL· GenBank· DDBJ
AAH63942.1
EMBL· GenBank· DDBJ
mRNA
AF091593
EMBL· GenBank· DDBJ
AAC64289.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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