Q5SY34 · Q5SY34_HUMAN

  • Protein
    dual-specificity kinase
  • Gene
    DYRK3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site218ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentintracellular membrane-bounded organelle
Cellular Componentnucleoplasm
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionprotein serine/threonine/tyrosine kinase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dual-specificity kinase
  • EC number

Gene names

    • Name
      DYRK3

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q5SY34

Proteomes

Organism-specific databases

Disease & Variants

Variants

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The viewer provides 234 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)86PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region77-117Disordered
Domain189-243Protein kinase

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    243
  • Mass (Da)
    27,610
  • Last updated
    2004-12-21 v1
  • Checksum
    45463772AD988542
MKWKEKLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQ

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
O43781DYRK3_HUMANDYRK3588
A0A3B3ISB2A0A3B3ISB2_HUMANDYRK371

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue243

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL591846
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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