Dysfunction of programmed embryo senescence is linked to genetic developmental defects.de Lope C., Garcia-Lucena R., Magarinos M., Leon Y., Casa-Rodriguez N., Contreras N., Escudero-Iriarte C., Varela-Nieto I., Maire P., Palmero I.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97450PubMedEurope PMCDevelopment 150:dev200903-dev200903 (2023)Mapped to62
Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling.Qiu T., Huteckova B., Seppala M., Cobourne M.T., Chen Z., Hovorakova M., Buchtova M., Tucker A.S.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDevelopment 150:dev201464-dev201464 (2023)Mapped to99+
Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle for inner ear development.Song H., Morrow B.E.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDev Biol 494:71-84 (2023)Mapped to89
Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons.Du H., Wang Z., Guo R., Yang L., Liu G., Zhang Z., Xu Z., Tian Y., Yang Z.[...], Chen B.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCCereb Cortex 32:3611-3632 (2022)Mapped to99+
Phase transition specified by a binary code patterns the vertebrate eye cup.Balasubramanian R., Min X., Quinn P.M.J., Giudice Q.L., Tao C., Polanco K., Makrides N., Peregrin J., Bouaziz M.[...], Zhang X.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCSci Adv 7:eabj9846-eabj9846 (2021)Mapped to99+
mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Muller glia.Lim S., Kim Y.J., Park S., Choi J.H., Sung Y.H., Nishimori K., Kozmik Z., Lee H.W., Kim J.W.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCElife 10:e70079-e70079 (2021)Mapped to99+
Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse.Kaiser M., Wojahn I., Rudat C., Luedtke T.H., Christoffels V.M., Moon A., Kispert A., Trowe M.O.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDevelopment 148:0-0 (2021)Cited in2Mapped to99+
The transcription factor <i>Maz</i> is essential for normal eye development.Medina-Martinez O., Haller M., Rosenfeld J.A., O'Neill M.A., Lamb D.J., Jamrich M.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDis Model Mech 13:dmm044412-dmm044412 (2020)Mapped to93
Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation.Diacou R., Zhao Y., Zheng D., Cvekl A., Liu W.View abstractCategoriesFunction, ExpressionSourceMGI: 97450PubMedEurope PMCCell Rep 25:2510-2523.e4 (2018)Mapped to99+
Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer.Botella-Lopez A., Garcia-Lopez R., Pombero A., Martinez S.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCBrain Struct Funct 224:661-679 (2019)Mapped to99+
Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.Iwai-Takekoshi L., Balasubramanian R., Sitko A., Khan R., Weinreb S., Robinson K., Mason C.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDevelopment 145:dev163212-dev163212 (2018)Mapped to99+
A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of <i>Tsc1</i> disrupts ciliary body and iris development.Hagglund A.C., Jones I., Carlsson L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97450PubMedEurope PMCDis Model Mech 10:245-257 (2017)Mapped to64
Msx1-Positive Progenitors in the Retinal Ciliary Margin Give Rise to Both Neural and Non-neural Progenies in Mammals.Belanger M.C., Robert B., Cayouette M.View abstractCategoriesFunction, Sequences, ExpressionSourceMGI: 97450PubMedEurope PMCDev Cell 40:137-150 (2017)Mapped to74
Meis1 coordinates a network of genes implicated in eye development and microphthalmia.Marcos S., Gonzalez-Lazaro M., Beccari L., Carramolino L., Martin-Bermejo M.J., Amarie O., Mateos-San Martin D., Torroja C., Bogdanovic O.[...], Bovolenta P.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDevelopment 142:3009-3020 (2015)Mapped to79
Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.Metzakopian E., Bouhali K., Alvarez-Saavedra M., Whitsett J.A., Picketts D.J., Ang S.L.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDevelopment 142:1315-1324 (2015)Mapped to99+
SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice.Wu Q., Fukuda K., Weinstein M., Graff J.M., Saga Y.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDevelopment 142:575-586 (2015)Mapped to93
Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling.Heavner W.E., Andoniadou C.L., Pevny L.H.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCNeural Dev 9:27-27 (2014)Mapped to75
Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.Gerstmann K., Pensold D., Symmank J., Khundadze M., Hubner C.A., Bolz J., Zimmer G.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDevelopment 142:140-150 (2015)Mapped to99+
Role of heparan sulfate proteoglycans in optic disc and stalk morphogenesis.Cai Z., Grobe K., Zhang X.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97450PubMedEurope PMCDev Dyn 243:1310-1316 (2014)Mapped to74
Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma.Cai Z., Tao C., Li H., Ladher R., Gotoh N., Feng G.S., Wang F., Zhang X.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97450PubMedEurope PMCDevelopment 140:2711-2723 (2013)Mapped to99+
Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye.Zhou Y., Tanzie C., Yan Z., Chen S., Duncan M., Gaudenz K., Li H., Seidel C., Lewis B.[...], Xie T.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCProc Natl Acad Sci U S A 110:8966-8971 (2013)Mapped to94
Retinoic acid deficiency impairs the vestibular function.Romand R., Krezel W., Beraneck M., Cammas L., Fraulob V., Messaddeq N., Kessler P., Hashino E., Dolle P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97450PubMedEurope PMCJ. Neurosci. 33:5856-5866 (2013)Cited in1Mapped to99+
Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.Zou C., Levine E.M.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCPLoS Genet. 8:E1002924-E1002924 (2012)Cited in2Mapped to55
SOX2 hypomorphism disrupts development of the prechordal floor and optic cup.Langer L., Taranova O., Sulik K., Pevny L.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCMech Dev 129:1-12 (2012)Mapped to57
Redundant functions of Rac GTPases in inner ear morphogenesis.Grimsley-Myers C.M., Sipe C.W., Wu D.K., Lu X.View abstractCategoryFunctionSourceMGI: 97450PubMedEurope PMCDev Biol 362:172-186 (2012)Mapped to99+