Q5REZ7 · Q5REZ7_PONAB

Function

function

Catalyzes the final step in the metabolic pathway of hydroxyproline.

Catalytic activity

Features

Showing features for active site, binding site.

126620406080100120140160180200220240260
Type
IDPosition(s)Description
Active site107Proton donor/acceptor
Active site135Schiff-base intermediate with substrate
Binding site178pyruvate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Function(R,S)-4-hydroxy-2-oxoglutarate aldolase activity
Biological Processglyoxylate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxy-2-oxoglutarate aldolase, mitochondrial
  • EC number
  • Alternative names
    • Dihydrodipicolinate synthase-like
    • Probable 2-keto-4-hydroxyglutarate aldolase

Gene names

    • Name
      DKFZp469C2232

Organism names

Accessions

  • Primary accession
    Q5REZ7

Subcellular Location

Interaction

Subunit

Homotetramer.

Family & Domains

Sequence similarities

Belongs to the DapA family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    266
  • Mass (Da)
    28,750
  • Last updated
    2004-12-21 v1
  • Checksum
    75F810D6BE50F608
HKLGTFPFRGFVVQGSNGEFPFLTSSERLEVVSRVRQAMPKNRLLLAGSGCESTQATVEMTVSMAQVGADAAMVVTPCYYRGRMSSAALIHHYTKVADFSPIPVVLYSVPANTGLDLPVDAVVTLSQHPNIVGMKDSGGDVTRIGLIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVCALANVLGAQVCQLERLCCTGQWEEAQKLQHRLIEPNAAVTRRFGIPGLKKIMDWFGYYGGPCRAPLQELSPAEEEALRMDFTSNGWL

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR857365
EMBL· GenBank· DDBJ
CAH89660.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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