Q5RDI5 · Q5RDI5_PONAB

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site, active site.

111231002003004005006007008009001,0001,100
Type
IDPosition(s)Description
Binding site830-837ATP (UniProtKB | ChEBI)
Binding site854ATP (UniProtKB | ChEBI)
Active site963Proton acceptor
Binding site967ATP (UniProtKB | ChEBI)
Binding site968Mg2+ (UniProtKB | ChEBI)
Binding site981Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functiontransmembrane receptor protein tyrosine kinase activity
Biological Processangiogenesis
Biological Processcell differentiation
Biological Processcell surface receptor protein tyrosine kinase signaling pathway
Biological Processendothelial cell proliferation
Biological Processpositive regulation of angiogenesis
Biological Processpositive regulation of endothelial cell migration
Biological Processpositive regulation of kinase activity
Biological Processpositive regulation of MAPK cascade
Biological Processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • Name
      DKFZp469E064

Organism names

Accessions

  • Primary accession
    Q5RDI5

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane746-770Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-22
ChainPRO_500426246623-1123receptor protein-tyrosine kinase
Disulfide bond242↔251

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain216-252EGF-like
Domain350-440Ig-like
Domain447-541Fibronectin type-III
Domain545-636Fibronectin type-III
Domain641-735Fibronectin type-III
Domain823-1095Protein kinase

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,123
  • Mass (Da)
    125,654
  • Last updated
    2004-12-21 v1
  • Checksum
    E27ECC3E1E3EF9C9
MDSLASLVLCGVSLLLSGTVEGAMDLILINSLPLVSDAETSLTCIASGWRPHEPITIGRDFEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGEAIRIRTMKMRQQASFLPATLTMTVDKGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPECNHLCTACMNNGACHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPDPYGCSCATGRKGLQCNEACHPGFYGPDCKLRCSCNNGEMCDRFQGCLCSPGWQGLQCEREGIPRMTPKIVDLPDHIEVNSGKFNPICKASGWPLPTNEEMTLVKPDGTVLHPKDFNHTDHFSVAIFTIHRILPPDSGVWVCSVNTVAGMVEKPFNISVKVLPKPLNAPNVIDTGHNFAVINISSEPYFGDGPIKSKKLLYKPVNHYEAWQHIQVTNEIVTLNYLEPRTEYELCVQLLRRGEGGEGHPGPVRRFTTASIGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHIDVKIKNATITQYQLKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVPCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR857924
EMBL· GenBank· DDBJ
CAH90172.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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