Q5R4P1 · ATLA1_PONAB

Function

function

GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.

Features

Showing features for binding site.

155850100150200250300350400450500550
TypeIDPosition(s)Description
Binding site74-81GTP (UniProtKB | ChEBI)
Binding site118-120GTP (UniProtKB | ChEBI)
Binding site217-218GTP (UniProtKB | ChEBI)
Binding site276-279GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentaxon
Cellular Componentendoplasmic reticulum
Cellular Componentendoplasmic reticulum membrane
Cellular Componentendoplasmic reticulum tubular network
Cellular Componentendoplasmic reticulum tubular network membrane
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi cis cisterna
Cellular ComponentGolgi membrane
Cellular Componentmembrane
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionidentical protein binding
Biological Processaxonogenesis
Biological Processendoplasmic reticulum organization
Biological Processendoplasmic reticulum tubular network membrane organization
Biological Processprotein homooligomerization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      ATL1

Organism names

Accessions

  • Primary accession
    Q5R4P1
  • Secondary accessions
    • Q5RA74

Proteomes

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-449Cytoplasmic
Transmembrane450-470Helical
Topological domain471Lumenal
Transmembrane472-492Helical
Topological domain493-558Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00002504831-558Atlastin-1
Modified residue10Phosphoserine
Modified residue22Phosphoserine
Modified residue23Phosphoserine
Modified residue395N6-acetyllysine

Keywords

Interaction

Subunit

Monomer as apoprotein and in the GDP-bound form. Homodimer in the GTP-bound form. Interacts (via N-terminal region) with MAP4K4 (via CNH regulatory domain). Interacts with REEP5, RTN3 and RTN4 (via the transmembrane region). Interacts with SPAST; interaction is direct. Interacts with REEP1. Interacts with CPT1C. Interacts with ARL6IP1. Interacts with ZFYVE27.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain, coiled coil.

TypeIDPosition(s)Description
Region1-27Disordered
Domain64-309GB1/RHD3-type G
Coiled coil412-439
Region448-558Sufficient for membrane association

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    558
  • Mass (Da)
    63,544
  • Last updated
    2006-10-03 v2
  • Checksum
    68A33C39DD43504C
MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8I5TKP0A0A8I5TKP0_PONABATL1537
A0A2J8WKG9A0A2J8WKG9_PONABATL1553

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict30in Ref. 1; CAH93275

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR859145
EMBL· GenBank· DDBJ
CAH91336.1
EMBL· GenBank· DDBJ
mRNA
CR861204
EMBL· GenBank· DDBJ
CAH93275.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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