Q5QVW3 · DCUP_IDILO
- ProteinUroporphyrinogen decarboxylase
- GenehemE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids358 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Catalytic activity
- uroporphyrinogen III + 4 H+ = coproporphyrinogen III + 4 CO2
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 29-33 | substrate | |||
Binding site | 79 | substrate | |||
Site | 79 | Transition state stabilizer | |||
Binding site | 156 | substrate | |||
Binding site | 211 | substrate | |||
Binding site | 329 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | uroporphyrinogen decarboxylase activity | |
Biological Process | protoporphyrinogen IX biosynthetic process from glutamate |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUroporphyrinogen decarboxylase
- EC number
- Short namesUPD ; URO-D
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Idiomarinaceae > Idiomarina
Accessions
- Primary accessionQ5QVW3
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000325656 | 1-358 | Uroporphyrinogen decarboxylase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length358
- Mass (Da)39,158
- Last updated2005-01-04 v1
- ChecksumFC1FD32C0A31AD32
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE017340 EMBL· GenBank· DDBJ | AAV83138.1 EMBL· GenBank· DDBJ | Genomic DNA |