Q5QVW3 · DCUP_IDILO

Function

function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Features

Showing features for binding site, site.

135850100150200250300350
Type
IDPosition(s)Description
Binding site29-33substrate
Binding site79substrate
Site79Transition state stabilizer
Binding site156substrate
Binding site211substrate
Binding site329substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionuroporphyrinogen decarboxylase activity
Biological Processprotoporphyrinogen IX biosynthetic process from glutamate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uroporphyrinogen decarboxylase
  • EC number
  • Short names
    UPD
    ; URO-D

Gene names

    • Name
      hemE
    • Ordered locus names
      IL2306

Organism names

Accessions

  • Primary accession
    Q5QVW3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003256561-358Uroporphyrinogen decarboxylase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    358
  • Mass (Da)
    39,158
  • Last updated
    2005-01-04 v1
  • Checksum
    FC1FD32C0A31AD32
MTAPALKNDRYLRALAKQPVDRTPVWMMRQAGRYLPEYKEVRGQAGDFMSLCRNTELACEVTMQPLRRFDLDAAILFSDILTIPDAMGLGLYFEAGEGPKFKDPVRSMAAIKNLAVPDMEDELGYVMDAVRAIRRELNGSVPLIGFSGSPWTLATYMVEGGSTKNFSKVKQLMFADPEAMHTLLNVLAESVTQYLNAQIAAGAQSVMIFDTWGGVLSPRDYKAFSLAYMEKIVAGLTREADGRKVPVTLFTKNGGQWLEAMAASGADALGVDWTTDLSDARARVGGQVALQGNMDPSVLYAKPARIEEEVQSILQSYGSGTGHVFNLGHGIHPEVDPEHAAAFIEAIHKYSPAFHSND

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE017340
EMBL· GenBank· DDBJ
AAV83138.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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