Q5QVP2 · PEPQ2_IDILO

Function

function

Splits dipeptides with a prolyl residue in the C-terminal position.

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 manganese ions per subunit.

Features

Showing features for binding site.

143850100150200250300350400
TypeIDPosition(s)Description
Binding site242Mn2+ 2 (UniProtKB | ChEBI)
Binding site253Mn2+ 1 (UniProtKB | ChEBI)
Binding site253Mn2+ 2 (UniProtKB | ChEBI)
Binding site333Mn2+ 1 (UniProtKB | ChEBI)
Binding site378Mn2+ 1 (UniProtKB | ChEBI)
Binding site414Mn2+ 1 (UniProtKB | ChEBI)
Binding site414Mn2+ 2 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionaminopeptidase activity
Molecular Functionmetal ion binding
Molecular Functionmetalloexopeptidase activity
Molecular Functionphosphoric triester hydrolase activity
Molecular Functionproline dipeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Xaa-Pro dipeptidase 2
  • EC number
  • Short names
    X-Pro dipeptidase 2
  • Alternative names
    • Imidodipeptidase 2
    • Proline dipeptidase 2
      (Prolidase 2
      )

Gene names

    • Name
      pepQ2
    • Ordered locus names
      IL2239

Organism names

Accessions

  • Primary accession
    Q5QVP2

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003038481-438Xaa-Pro dipeptidase 2

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    438
  • Mass (Da)
    50,041
  • Last updated
    2005-01-04 v1
  • Checksum
    06ACA8DB02ECAFCC
MSAYAEHIKTVCSRFDKALEDNNFESVLVYSGQPRVDFLDDNAPPYRVNPLFKYWVPVTESPKSAIFYRKGSQRPTVYLFQARDFWHAPVNVPEEEWQQHVDLKIIDDLSMLTEDLGSDLEQSAFIGEDFAQPVSDWRVKARNPQALIDHLHFHRSIKTQWEVDNLREANRLAAKAHVAAKEAFFAGKSELEIHHAYLGAIDFRESQVPYNSIVALNSHSAILHYDVYDTVPPKQIRSFLIDAGARYRGYCSDITRSYAYEEGFYANLVEAMDKAQQELLSEIKPGVSYYDLHVSMHLKVAQILSDFEFIKGDAQSIYDKGYTSAFMPHGLGHFIGLQVHDVGGFLKDDKGNSYERSERHPFLRLLRDIEVGHVFTIEPGLYVVDQLLEEHKDSADINWEKVDELRPYGGVRIEDSIVVGADGNENLTRDAFKELGAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE017340
EMBL· GenBank· DDBJ
AAV83071.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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