Q5NDL3 · EOGT_CHICK

  • Protein
    EGF domain-specific O-linked N-acetylglucosamine transferase
  • Gene
    EOGT
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum lumen
Molecular Functionprotein O-acetylglucosaminyltransferase activity
Biological Processprotein O-GlcNAcylation via threonine
Biological Processprotein O-linked glycosylation

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    EGF domain-specific O-linked N-acetylglucosamine transferase
  • EC number
  • Alternative names
    • Extracellular O-linked N-acetylglucosamine transferase

Gene names

    • Name
      EOGT
    • Synonyms
      AER61

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus

Accessions

  • Primary accession
    Q5NDL3

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-16
ChainPRO_000030197517-535EGF domain-specific O-linked N-acetylglucosamine transferase
Glycosylation22N-linked (GlcNAc...) asparagine
Glycosylation271N-linked (GlcNAc...) asparagine
Glycosylation362N-linked (GlcNAc...) asparagine
Glycosylation501N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif303-305Required for optimal activity

Sequence similarities

Belongs to the glycosyltransferase 61 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    535
  • Mass (Da)
    62,868
  • Last updated
    2007-09-11 v2
  • Checksum
    2F0EC0F588B4BB3B
MFILLMFVLLLQEILANSRDENLTELNSVLEEPTYSYRAINLPAEHIPYFLHNNRHIAGICKQDSRCPYKVGFYFVLHKYLKKLKSCWGYEKSCKSDYRFSYPVCDYVESGWANDIETAQQIFWKQADFGYIRERLNEMKTHCKPTVTGDSSLTCSQFLQHCRATNLYIDLRTAKRNHERFKEDFFQKGEIGGHCTLDVKAFLAEGQRKSPLQSWFAELQTFTSLNFRPLDDGKCDIVIEKPTYFMKLDAGVNMYHHFCDFVNLYITQHINNSFSTDVNIVMWDTSSYGYGDLFSETWKAFTDYDIIYLKTFDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCHGTGLFRAFSQHVLHRLNITQEGPKDGKIRVTILARSTDYRKILNQNELVNALKTVSTLEVKVVDYKYKELEFSEQLRITHNSDIFIGMHGAGLTHLLFLPDWAVVFELYNCEDERCYLDLARLRGIHYITWRKRNKVFPQDQGHHPTLGEHPKFTNYSFDVEEFMYLVLLAANHVSQHSKWPFRVKHDEF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BU415425
EMBL· GenBank· DDBJ
-mRNA No translation available.
AJ868233
EMBL· GenBank· DDBJ
CAI30568.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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