Q5L1U9 · Q5L1U9_GEOKA
- ProteinOrnithine carbamoyltransferase
- GeneargF
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids312 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
Catalytic activity
- carbamoyl phosphate + L-ornithine = L-citrulline + phosphate + H+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 59-62 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 86 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 110 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 137-140 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 168 | L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 232 | L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 236-237 | L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 272-273 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 300 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | amino acid binding | |
Molecular Function | ornithine carbamoyltransferase activity | |
Biological Process | arginine biosynthetic process via ornithine | |
Biological Process | citrulline biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameOrnithine carbamoyltransferase
- EC number
- Short namesOTCase
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Geobacillus > Geobacillus thermoleovorans group
Accessions
- Primary accessionQ5L1U9
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 10-150 | Aspartate/ornithine carbamoyltransferase carbamoyl-P binding | |||
Domain | 156-310 | Aspartate/ornithine carbamoyltransferase Asp/Orn-binding | |||
Sequence similarities
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length312
- Mass (Da)33,697
- Last updated2005-02-01 v1
- MD5 ChecksumFE606979E9D108EBFC73E065EBF665D1
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000043 EMBL· GenBank· DDBJ | BAD75081.1 EMBL· GenBank· DDBJ | Genomic DNA |