Q5L199 · Q5L199_GEOKA

Function

function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site190Tele-phosphohistidine intermediate
Binding site297phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site333phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site432Mg2+ (UniProtKB | ChEBI)
Binding site455-456phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site456Mg2+ (UniProtKB | ChEBI)
Binding site466phosphoenolpyruvate (UniProtKB | ChEBI)
Active site503Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoenolpyruvate-protein phosphotransferase activity
Biological Processphosphoenolpyruvate-dependent sugar phosphotransferase system

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate-protein phosphotransferase
  • EC number
  • Alternative names
    • Phosphotransferase system, enzyme I

Gene names

    • Name
      ptsI
    • Ordered locus names
      GK0996

Organism names

Accessions

  • Primary accession
    Q5L199

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain6-127Phosphotransferase system enzyme I N-terminal
Coiled coil27-61
Domain154-226PEP-utilising enzyme mobile
Domain251-541PEP-utilising enzyme C-terminal

Sequence similarities

Belongs to the PEP-utilizing enzyme family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    573
  • Mass (Da)
    63,021
  • Last updated
    2005-02-01 v1
  • Checksum
    D1E72B9FDA0A273E
MEKTIHGIAASSGIAIAKAYRLETPHLAAEKRTVADVEAEIARLEAAVAKAKEELEAIKQHALEKLGEDKAAIFAAHLLVLDDPELLNPIKEKIKTEQVNAEYALHETASFFISMFEGMDNEYMKERAADIRDVTKRVLAHLLGVTISNPSLISEEVVIIAEDLTPSDTAQLNRQYVKGFATDIGGRTSHSAIMARSLEIPAVVGTKAITAEVQNGDIVIVDGLDGQVVVNPSPELLARYEEKRARYEEQKAEWAKLVDQPTVTADGVHVELAANIGTPDDVKGALANGAEGIGLYRTEFLYMGRSELPTEDEQFAAYKTVLEQMGGKPVVVRTLDIGGDKELPYLHLPKEMNPFLGFRAIRLCLEMQDMFRTQLRALLRASVHGNLKIMFPMIATLDEFRQAKAILLEEKEALLRQGVPVADGIEVGMMVEIPAAAVMADQFAREVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYNPAILRLISYVIDAAHREGKWVGMCGEMAGDPIAIPILLALGLDEFSMSATSILPARAQLKRLSKEDAVCVKETVLSLGTAEEVVSFVKRTFHMA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000043
EMBL· GenBank· DDBJ
BAD75281.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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