Q5K2W1 · Q5K2W1_9CYAN

Function

function

An RbcL-specific chaperone. The central cleft of the RbcX homodimer (RbcX2) binds the C-terminus of an RbcL monomer, stabilizing the C-terminus and probably preventing its reassociation with chaperonin GroEL-ES. At the same time the peripheral region of RbcX2 binds a second RbcL monomer, bridging the RbcL homodimers in the correct orientation. The RbcX22-bound RbcL dimers then assemble into the RbcL8 core (RbcL8-(RbcX2)8). RbcS binding triggers the release of RbcX2.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcarboxysome
Cellular Componentcytoplasm
Molecular Functionprotein folding chaperone
Biological Processcarbon fixation
Biological Processphotosynthesis
Biological Processribulose bisphosphate carboxylase complex assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    RuBisCO chaperone RbcX

Gene names

    • Name
      rbcX

Organism names

  • Taxonomic identifier
  • Strains
    • PCC 7804
    • SAG 50.79
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Aphanizomenonaceae > Nodularia

Accessions

  • Primary accession
    Q5K2W1

Subcellular Location

Carboxysome
Cytoplasm
Note: Most protein is cytoplasmic, but some is in the carboxysome.

Keywords

Interaction

Subunit

Homodimer. Interacts with the exposed C-terminal peptide of RbcL via its central cleft, contacts a second RbcL monomer via its peripheral polar surface.

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region97-135Disordered
Compositional bias100-114Basic and acidic residues
Compositional bias115-129Polar residues

Domain

The homodimer has 2 functional domains, a central cleft essential for production of soluble RbcL in which the RbcL peptide binds, and a polar surface which plays a role in correct RbcL subunit arrangement.

Sequence similarities

Belongs to the RbcX family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    135
  • Mass (Da)
    15,595
  • Last updated
    2005-02-15 v1
  • Checksum
    D8E971FF444B3A59
MNLKQIAKDTAKTLQSYLTYQALKTVLAQLGETNPPLELWLHNFSAGKIQDGEAYIQQLFLEKPDLALRIMTVREHIAEEVADFLPEMVRTGFQQANMEQRRQHLERMTRIDTSHPSPHPEQQTSSDFNSDSDHF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias100-114Basic and acidic residues
Compositional bias115-129Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ185302
EMBL· GenBank· DDBJ
ABB77525.1
EMBL· GenBank· DDBJ
Genomic DNA
KF010335
EMBL· GenBank· DDBJ
AGU03178.1
EMBL· GenBank· DDBJ
Genomic DNA
AJ783695
EMBL· GenBank· DDBJ
CAH04080.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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