Q5JKF2 · RH40_ORYSJ
- ProteinDEAD-box ATP-dependent RNA helicase 40
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids792 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 194-201 | ATP (UniProtKB | ChEBI) | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Cellular Component | ribonucleoprotein complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | mRNA binding | |
Molecular Function | RNA helicase activity | |
Biological Process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | |
Biological Process | rRNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDEAD-box ATP-dependent RNA helicase 40
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionQ5JKF2
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue (large scale data).
Type | ID | Position(s) | Source | Description | ||
---|---|---|---|---|---|---|
Chain | PRO_0000282457 | 1-792 | UniProt | DEAD-box ATP-dependent RNA helicase 40 | ||
Modified residue (large scale data) | 86 | PTMeXchange | Phosphothreonine | |||
Modified residue (large scale data) | 550 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 552 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 588 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 608 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 656 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 658 | PTMeXchange | Phosphothreonine | |||
Modified residue (large scale data) | 660 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 675 | PTMeXchange | Phosphothreonine | |||
Modified residue (large scale data) | 688 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 709 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 720 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 728 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 730 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 732 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 753 | PTMeXchange | Phosphoserine | |||
Modified residue (large scale data) | 754 | PTMeXchange | Phosphoserine | |||
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-25 | Disordered | |||
Domain | 17-51 | WW | |||
Region | 44-118 | Disordered | |||
Compositional bias | 51-68 | Pro residues | |||
Compositional bias | 69-112 | Basic and acidic residues | |||
Motif | 150-178 | Q motif | |||
Domain | 181-355 | Helicase ATP-binding | |||
Motif | 303-306 | DEAD box | |||
Domain | 384-528 | Helicase C-terminal | |||
Region | 523-792 | Disordered | |||
Compositional bias | 529-558 | Basic and acidic residues | |||
Compositional bias | 573-610 | Basic and acidic residues | |||
Compositional bias | 611-646 | Basic residues | |||
Compositional bias | 667-710 | Basic and acidic residues | |||
Compositional bias | 713-748 | Polar residues | |||
Domain
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence similarities
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q5JKF2-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length792
- Mass (Da)87,980
- Last updated2007-04-03 v2
- ChecksumB0A866D5D26EBBFC
Q5JKF2-2
- Name2
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0P0V3W4 | A0A0P0V3W4_ORYSJ | Os01g0549400 | 639 | ||
A0A0P0V3W9 | A0A0P0V3W9_ORYSJ | Os01g0549400 | 266 |
Features
Showing features for alternative sequence, compositional bias, sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Alternative sequence | VSP_024159 | 1-141 | in isoform 2 | ||
Compositional bias | 51-68 | Pro residues | |||
Compositional bias | 69-112 | Basic and acidic residues | |||
Alternative sequence | VSP_024160 | 142-164 | in isoform 2 | ||
Sequence conflict | 344 | in Ref. 6; AK122104 | |||
Sequence conflict | 512 | in Ref. 6; AK102720 | |||
Compositional bias | 529-558 | Basic and acidic residues | |||
Compositional bias | 573-610 | Basic and acidic residues | |||
Compositional bias | 611-646 | Basic residues | |||
Compositional bias | 667-710 | Basic and acidic residues | |||
Compositional bias | 713-748 | Polar residues | |||
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP004225 EMBL· GenBank· DDBJ | BAD88050.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP004225 EMBL· GenBank· DDBJ | BAD88051.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP008207 EMBL· GenBank· DDBJ | BAF05209.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP014957 EMBL· GenBank· DDBJ | BAS72626.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP014957 EMBL· GenBank· DDBJ | BAS72627.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CM000138 EMBL· GenBank· DDBJ | EAZ12284.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK102720 EMBL· GenBank· DDBJ | - | mRNA | No translation available. | |
AK122104 EMBL· GenBank· DDBJ | - | mRNA | No translation available. |