Q5J6J2 · SCPB_TRIRU

Function

function

Extracellular serine carboxypeptidase that contributes to pathogenicity.

Catalytic activity

  • Preferential release of a C-terminal arginine or lysine residue.
    EC:3.4.16.6 (UniProtKB | ENZYME | Rhea)

pH Dependence

Optimum pH is 8.0.

Features

Showing features for active site, binding site.

166250100150200250300350400450500550600650
Type
IDPosition(s)Description
Active site240
Active site459
Binding site462substrate
Active site517
Binding site518substrate

GO annotations

AspectTerm
Cellular Componentfungal-type vacuole
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular Functionserine-type carboxypeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Carboxypeptidase S1 homolog B
  • EC number
  • Alternative names
    • Serine carboxypeptidase B (SPCB)

Gene names

    • Name
      SCPB

Organism names

Accessions

  • Primary accession
    Q5J6J2

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation, lipidation, propeptide.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_000038412322-633Carboxypeptidase S1 homolog B
Disulfide bond51↔123
Glycosylation130N-linked (GlcNAc...) asparagine
Glycosylation163N-linked (GlcNAc...) asparagine
Glycosylation186N-linked (GlcNAc...) asparagine
Glycosylation200N-linked (GlcNAc...) asparagine
Glycosylation262N-linked (GlcNAc...) asparagine
Glycosylation302N-linked (GlcNAc...) asparagine
Glycosylation311N-linked (GlcNAc...) asparagine
Disulfide bond328↔364
Disulfide bond335↔357
Glycosylation350N-linked (GlcNAc...) asparagine
Glycosylation414N-linked (GlcNAc...) asparagine
Glycosylation475N-linked (GlcNAc...) asparagine
Glycosylation493N-linked (GlcNAc...) asparagine
Glycosylation506N-linked (GlcNAc...) asparagine
Glycosylation598N-linked (GlcNAc...) asparagine
Glycosylation612N-linked (GlcNAc...) asparagine
Lipidation633GPI-anchor amidated glycine
PropeptidePRO_0000384124634-662Removed in mature form

Keywords

PTM databases

Expression

Induction

Expression is strongly increased during growth on protein-rich medium.

Structure

Family & Domains

Sequence similarities

Belongs to the peptidase S10 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    662
  • Mass (Da)
    73,012
  • Last updated
    2005-02-15 v1
  • Checksum
    B47308AB5BB82CCB
MVSFCGVAACLLTVAGHLAQAQFPPKPEGVTVLESKFGSGARITYKEPGLCETTEGVKSYAGYVHLPPGTLRDFGVEQDYPINTFFWFFEARKDPENAPLGIWMNGGPGSSSMFGMMTENGPCFVNADSNSTRLNPHSWNNEVNMLYIDQPVQVGLSYDTLANFTRNLVTDEITKLKPGEPIPEQNATFLVGTYASRNMNTTAHGTRHAAMALWHFAQVWFQEFPGYHPRNNKISIATESYGGRYGPAFTAFFEEQNQKIKNGTWKGHEGTMHVLHLDTLMIVNGCIDRLVQWPAYPQMAYNNTYSIEAVNASIHAGMLDALYRDGGCRDKINHCRSLSSVFDPENLGINSTVNDVCKDAETFCSNDVRDPYLKFSGRNYYDIGQLDPSPFPAPFYMAWLNQPHVQAALGVPLNWTQSNDVVSTAFRAIGDYPRPGWLENLAYLLENGIKVSLVYGDRDYACNWFGGELSSLGINYTDTHEFHNAGYAGIQINSSYIGGQVRQYGNLSFARVYEAGHEVPSYQPETALQIFHRSLFNKDIATGTKDTSSRMDGGKFYGTSGPADSFGFKNKPPPQHVHFCHILDTSTCTKEQIQSVENGTAAVRSWIIVDSNSTSLFPEVVGSGEPTPTPMPGGATTLSAHGFLYGVTLWAVIVVAVIELAM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY497022
EMBL· GenBank· DDBJ
AAS76666.1
EMBL· GenBank· DDBJ
Genomic DNA

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