Q5ILI9 · Q5ILI9_HETPA

Function

Catalytic activity

Cofactor

Cu cation (UniProtKB | Rhea| CHEBI:23378 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrion
Cellular Componentrespiratory chain complex IV
Molecular Functioncopper ion binding
Molecular Functioncytochrome-c oxidase activity
Molecular Functionheme binding
Biological Processaerobic respiration
Biological Processelectron transport chain

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    cytochrome-c oxidase
  • EC number

Gene names

    • Name
      cox1/2

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    Q5ILI9

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane37-56Helical
Transmembrane76-101Helical
Transmembrane121-147Helical
Transmembrane167-190Helical
Transmembrane202-229Helical
Transmembrane262-280Helical
Transmembrane292-309Helical
Transmembrane321-343Helical
Transmembrane355-375Helical
Transmembrane395-415Helical
Transmembrane436-457Helical
Transmembrane477-501Helical
Transmembrane521-540Helical
Transmembrane560-580Helical
Transmembrane614-638Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain25-500Cytochrome oxidase subunit I profile
Domain534-642Cytochrome oxidase subunit II transmembrane region profile
Domain643-778Cytochrome oxidase subunit II copper A binding

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    778
  • Mass (Da)
    87,551
  • Last updated
    2005-02-15 v1
  • Checksum
    E601A76E896AB3ED
MKIIEIYDRTRVKKKDLLSVFLNKWIFTVDHKLIGQLYLIFSILAGIIGTLLSLIIRLELSTGTMLDGDSQLFNVIITSHGLIMIFFMVMPAMLGGFGNWFVPIMIGAPDMAFPRLNNISFWLLVVSFILLLTSSFLGIGAGTGWTLYPPLSTMEYHPGVSVDVGILSLHIAGASSLLGAINFVTTIMNMKIAGLKYRKMSLFVWSVLITAILLILSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLISIILAKYSQKGIFGVKGMIAAMLAIGALGFIVWAHHMYTVGMDVDTRAYFTSATMIIAIPTGIKIFSWLATIWGGYIRITTASLFALGFLILFTIGGLTGIILSNGGLDISLHDTYYVVAHFHYVLSMGAVFAIFAAYYFFFSIINSTKAFGIVHYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRISDYPDAFVYWNLVASYGSLITAIGLLFFFANVFIAYIRPTTNINEQLKNLNIKKETVLKSVLGLISILDISRAGQIGFQDPATPIMEGIIDLHNFIFFYLIIVSVFIGWVFIRILWRFSYKWRYPEKGDMKIFSQFLVYNKIAHGTAIEICWTLIPTIILYVIAIPSFTLLYAMDEILTPTITIKIIGHQWYWSYEYSDDLNKQIEFDSYMVYEADLQEGQLRLLEVDNPMIVPIKTHIRLIITSEDVLHSWTVPSFGIKVDAVPGRLNQIGLYVKRPGVFYGQCSELCGVDHGFMPIKVKAVSIGKYLKTLYE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY700145
EMBL· GenBank· DDBJ
AAU00621.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp