Q5FQ60 · SYDND_GLUOX

Function

function

Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).

Catalytic activity

Features

Showing features for site, binding site.

159850100150200250300350400450500550
TypeIDPosition(s)Description
Site33Important for tRNA non-discrimination
Binding site175L-aspartate (UniProtKB | ChEBI)
Binding site221L-aspartate (UniProtKB | ChEBI)
Binding site221-223ATP (UniProtKB | ChEBI)
Binding site452L-aspartate (UniProtKB | ChEBI)
Binding site486ATP (UniProtKB | ChEBI)
Binding site493L-aspartate (UniProtKB | ChEBI)
Binding site538-541ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionaspartate-tRNA ligase activity
Molecular Functionaspartate-tRNA(Asn) ligase activity
Molecular FunctionATP binding
Molecular Functionnucleic acid binding
Biological Processaspartyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartate--tRNA(Asp/Asn) ligase
  • EC number
  • Alternative names
    • Aspartyl-tRNA synthetase
      (AspRS
      )
    • Non-discriminating aspartyl-tRNA synthetase
      (ND-AspRS
      )

Gene names

    • Name
      aspS
    • Ordered locus names
      GOX1747

Organism names

Accessions

  • Primary accession
    Q5FQ60

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001108781-598Aspartate--tRNA(Asp/Asn) ligase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region199-202Aspartate

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    598
  • Mass (Da)
    66,287
  • Last updated
    2005-03-01 v1
  • Checksum
    D6FBBA26A23AF058
MHPYRTHDCSALREENAGQVVRLSGWVHSKRDHGGLLFIDLRDHYGVTQIVIPAGTDLLEKAERLRVESVITVTGKVVVRHGSQRNPNLPTGDVEVLADALEVRSSAEVLPFQVAGNENYPEDLRLKYRYIDLRRDKMHQNIMLRSKVITSLRQRMIEQGFTEFQTPILTASSPEGARDFLVPARLHPGKFYALPQAPQQFKQLAMVAGFDRYFQIAPCFRDEASRADRSPGEFYQLDFEMSFVTQEDVFTVLEPVLAGVFNEFTPEGWKITDGAFPRIPYADAMRDYGSDKPDLRNPLIIKDVTDAFRDSGFGLFAKIAASGGQIRAIPAPGAGDRPRGFFDKLNSWARENGAGGLGYIIFGEEGGKGPIVKNLEADRVESIREICGLKAGDAVFFAAGKGDEVAKFSGVVRTKVATELDLIEKNAFRFCWVVDFPMYELNEETGKVDFSHNPFSMPQGGLEALNTQDPLTINAYQYDIVCNGVELSSGAIRNHLPDVMLRAFEIAGYGPEVVEERFGGMLNAFRYGAPPHGGAAPGVDRIVMLLADEPNIREVILFPLNQSGEDLMMEAPAPVEPARLKELHLALDLPKPKPTASK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000009
EMBL· GenBank· DDBJ
AAW61486.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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