Q5FJH4 · Q5FJH4_LACAC

Function

function

Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentprimosome complex
Molecular Function3'-5' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular Functionhydrolase activity
Molecular Functionzinc ion binding
Biological ProcessDNA recombination
Biological ProcessDNA replication initiation
Biological ProcessDNA replication, synthesis of primer
Biological ProcessDNA unwinding involved in DNA replication
Biological Processdouble-strand break repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Primosomal protein N'
  • EC number
  • Alternative names
    • ATP-dependent helicase PriA

Gene names

    • Name
      priA
    • Ordered locus names
      LBA1323

Organism names

Accessions

  • Primary accession
    Q5FJH4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Component of the primosome.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, zinc finger.

TypeIDPosition(s)Description
Domain277-443Helicase ATP-binding
Zinc finger505-517C4-type
Zinc finger532-548C4-type
Domain540-694Helicase C-terminal

Sequence similarities

Belongs to the helicase family. PriA subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    799
  • Mass (Da)
    91,208
  • Last updated
    2005-03-01 v1
  • Checksum
    1BFF3E450A9FC0FB
MIAKVVVDVAAKQTDRIFEYHIPVELEKDIKVGSRVVVPFGPRKIQGFVVGLSEDSEFKGQLKDLLVVVDEMPPLTPELVTLSADLAENIYSYRIKILQAMLPWVMRANYRKLLVPANAQAEKMQFFQGDPIDLNKITDLKDIKKIRKLLRDGDAKIEYVVENKAKKKKENQYELVLESEEYTKIYNTLRQNAVKQKQLLMDIIENEASYPKNQKDFEKKLGLTASVLNTAVKRGWLKRKEVEVYRDPLSGFKDNKKSAPVKLNDEQQFALNQITAAIDKRKAETFLLEGITGSGKTEVYLHAISKALEQGRNALMLVPEISLTPQMVRQVKSRFGQAVAVLHSALSEGEKYDEWRRIRRGETRVVVGARSAVFAPLDNIGLIVIDEEHESSYKQETDPRYNARDVAIWRSKYHHCPLVLGSATPSLGSRARAQKNVYKLLRLTKRANNKKLPKVNLIDLKHVQFAGGQFDLSVNLVDAIKKRLDNKEQVILMLNRRGFANFMLCRECGFVLKCPNCDVSLNLHKDTNSMQCHYCGHTERVPSRCPNCQSSKIRFLGTGTQKVQEELEELLPGARILRMDVDTTRKKGSYKRILDSFGNHEADILLGTQMIAKGLDFPNVTLVGVINADTGLWLSDYNASEKTFELLTQVAGRAGRANKEGEVLIQTYNPEHYAIQLAQTQNYERFYGYEMNVRHAGNYPPYFFTVLISIAAKKEQNAAREAFRIKRYLSQHLHEEMIILGPTPSAISRVKNQYYYQILVKYKKEPNIKELLHHIQDSAQEAKKYGLNVFIDNEPEKIM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000033
EMBL· GenBank· DDBJ
AAV43150.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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