Q5FIV6 · Q5FIV6_LACAC

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N1-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionphosphoribosylamine-glycine ligase activity
Biological Process'de novo' IMP biosynthetic process
Biological Processpurine nucleobase biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoribosylamine--glycine ligase
  • EC number
  • Alternative names
    • GARS
    • Glycinamide ribonucleotide synthetase
    • Phosphoribosylglycinamide synthetase

Gene names

    • Name
      purD
    • Ordered locus names
      LBA1551

Organism names

Accessions

  • Primary accession
    Q5FIV6

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain112-313ATP-grasp
Region215-235Disordered

Sequence similarities

Belongs to the GARS family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    423
  • Mass (Da)
    46,309
  • Last updated
    2005-03-01 v1
  • Checksum
    890A9600141CCB0E
MKDDLVLLVVGSGGREFAVAKKLKESPHVKTVYCAPGNVGMQTIGVETVPIEETDLDGLLDFAKSHNVDWTFVGPENVLCAGITDKFNKAGQKIFGPNQRAAQLEGSKDYALRFMSKYDIPTARYETYTSAETCIAGLKDFEYPVVIKEDGLAGGKGVTIAQNQDVAEETIREMFAGGQIAVVLEECLVGPEYSMFVVVSEDQFTILPMAQDHKRVGDGDKGPNTGGMGSYSPLPQLKKADRQRMIDEIVKPTMNGLVQGIYHYCGVLYIGLMMTESGPKVIEYNVRLGDPETQVVLPRIKNDFAMVIDAAVNHEKLPEIEENDNCVLGVVVCSKGYPTHPAPNVKIGKLPEGANTYIDYANVKGDLENLTGDGGRLFMVISEADNLVQAQDNVYSYLSKLDLLDCFYRHDIGNRALGDFNII

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000033
EMBL· GenBank· DDBJ
AAV43368.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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