Q5F829 · ISPD_NEIG1

Function

function

Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.

Features

Showing features for site.

122920406080100120140160180200220
TypeIDPosition(s)Description
Site17Transition state stabilizer
Site24Transition state stabilizer
Site158Positions MEP for the nucleophilic attack
Site212Positions MEP for the nucleophilic attack

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
  • EC number
  • Alternative names
    • 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
    • MEP cytidylyltransferase
      (MCT
      )

Gene names

    • Name
      ispD
    • Ordered locus names
      NGO_0972

Organism names

Accessions

  • Primary accession
    Q5F829

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002377991-2292-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    229
  • Mass (Da)
    24,467
  • Last updated
    2005-03-15 v1
  • Checksum
    49E86A75051231A9
MKRKNIALIPAAGIGVRFGADKPKQYVEIGSKTVLEHVLGIFERHEAVDLTVVVVSPEDTFADKVQTAFPQVRVWKNGGQTRAETVRNGVAKLLETGLAAETDNILVHDAARCCLPSEALARLIEQAGNAAEGGILAVPVADTLKRAESGQISATVDRSGLWQAQTPQLFQAGLLHRALAAENLGGITDEASAVEKLGVRPLLIQGDARNLKLTQPQDAYIVRLLLNAV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE004969
EMBL· GenBank· DDBJ
AAW89658.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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