Q5E924 · G3PP2_ARATH

Function

function

Involved in plastidial glycolytic pathway and plays a specific role in glycolytic energy production in non-green plastids and chloroplasts. Essential for breakdown of starch to form sucrose for export to non-photosynthetic tissues, and to generate primary metabolites for anabolic pathways such as fatty acid and amino acid synthesis. Plays an important role in plant development by providing substrates for the phosphorylated pathway of serine biosynthesis in roots. Plays a crucial role in pollen development. Functionally redundant with GAPCP1.

Catalytic activity

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site94-95NAD+ (UniProtKB | ChEBI)
Binding site116NAD+ (UniProtKB | ChEBI)
Binding site162NAD+ (UniProtKB | ChEBI)
Binding site233-235D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Active site234Nucleophile
Site261Activates thiol group during catalysis
Binding site264D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site293-294D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site316D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site398NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast stroma
Cellular Componentplastid
Molecular Functionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Molecular FunctionNAD binding
Molecular FunctionNADP binding
Biological Processcarbohydrate metabolic process
Biological Processglucose metabolic process
Biological Processglycolytic process
Biological Processintracellular amino acid homeostasis
Biological Processprimary root development

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glyceraldehyde-3-phosphate dehydrogenase GAPCP2, chloroplastic
  • EC number
  • Alternative names
    • Glyceraldehyde-3-phosphate dehydrogenase of plastid 2
    • NAD-dependent glyceraldehydephosphate dehydrogenase chloroplastic 2

Gene names

    • Name
      GAPCP2
    • ORF names
      F3O9.10
    • Ordered locus names
      At1g16300

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q5E924
  • Secondary accessions
    • Q84WR0
    • Q8L8W7
    • Q9SA29

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

No visible phenotype under normal growth conditions. Gapcp1 and gapcp2 double mutants have severe dwarf phenotypes with arrested root development and male sterility. Pollen grains show shrunken and collapsed forms and cannot germinate.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 27 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for transit peptide, chain.

TypeIDPosition(s)Description
Transit peptide1-66Chloroplast
ChainPRO_000042240867-420Glyceraldehyde-3-phosphate dehydrogenase GAPCP2, chloroplastic

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in shoot and root vasculature, leaf veins and vascular tissue of flowers and siliques.

Gene expression databases

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    420
  • Mass (Da)
    44,846
  • Last updated
    2005-03-15 v1
  • Checksum
    E9FF3D655F281B63
MALSSLLRSAATSAAAPRVELYPSSSYNHSQVTSSLGFSHSLTSSRFSGAAVSTGKYNAKRVQPIKATATEAPPAVHRSRSSGKTKVGINGFGRIGRLVLRIATFRDDIEVVAVNDPFIDAKYMAYMFKYDSTHGNYKGTINVIDDSTLEINGKQVKVVSKRDPAEIPWADLGAEYVVESSGVFTTVGQASSHLKGGAKKVIISAPSADAPMFVVGVNEKTYLPNMDIVSNASCTTNCLAPLAKVVHEEFGILEGLMTTVHATTATQKTVDGPSMKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTCRLEKDASYEDVKAAIKFASEGPLRGILGYTEEDVVSNDFLGDSRSSIFDANAGIGLSKSFMKLVSWYDNEWGYSNRVLDLIEHMALVAASR

Sequence caution

The sequence AAD34682.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict58in Ref. 3; AAO22684
Sequence conflict336in Ref. 5; AAM67077

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC006341
EMBL· GenBank· DDBJ
AAD34682.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002684
EMBL· GenBank· DDBJ
AEE29433.1
EMBL· GenBank· DDBJ
Genomic DNA
BT002867
EMBL· GenBank· DDBJ
AAO22684.1
EMBL· GenBank· DDBJ
mRNA
BT021096
EMBL· GenBank· DDBJ
AAX12866.1
EMBL· GenBank· DDBJ
mRNA
AY088762
EMBL· GenBank· DDBJ
AAM67077.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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