Q5E0J2 · Q5E0J2_ALIF1

Function

function

DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Biological Processcellular response to cold
Biological Processribosomal large subunit assembly
Biological ProcessRNA catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase DeaD
  • EC number
  • Alternative names
    • Cold-shock DEAD box protein A

Gene names

    • Name
      deaD
    • Synonyms
      csdA
    • Ordered locus names
      VF_A0384

Organism names

Accessions

  • Primary accession
    Q5E0J2

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, motif, region, compositional bias.

TypeIDPosition(s)Description
Domain6-34DEAD-box RNA helicase Q
Motif6-34Q motif
Domain37-208Helicase ATP-binding
Domain231-379Helicase C-terminal
Region449-483Disordered
Region566-634Disordered
Compositional bias587-634Basic and acidic residues

Sequence similarities

Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    634
  • Mass (Da)
    70,373
  • Last updated
    2005-03-15 v1
  • Checksum
    1F8F4153261FC71D
MSESITEFRQLALDESILSALDDMGFVAPTPIQAASIPLLLEGRDALGKAQTGTGKTAAFSLPLLNKINLKQHNPQAIIMAPTRELAIQVAAEVKNLGRNIKGLKVLEIYGGASIVDQMRALSRGAHIIVGTPGRVKDLLNRDRLNLGEVHTFILDEADEMLKMGFVDDVTWILEKAPDTAQRILFSATMPPMVKTIVDRYLREPARVDVAGTNHTVDKVEQNFWVVKGVEKDEAMSRLLETEETDASIVFVRTRQDTERLADWLSARGFKAAALHGDIPQSQRERTVDNIKNGVIDILVATDVVARGLDVPRITHVFNYDIPFDVESYIHRIGRTGRAGRKGKAILLVRTNQMRMLRTIERVTKSTMEEIQLPHRDQVAECRLAALAAELQADKEFVALDAFTDLINKLQETLEIDATTIAAMLLKRQQGKRPLFYKGPDPMIAAMERAKNRRSDRGERGERGGRGDRPERGERRQYNNDDFDTYQLEVGREQGVQVKDIVGALANELGFTKGSIGAIKLAPGHTYVQLPKKMSADVAGKLKKLRIRQNETKAVVVEGVDLTIERRPRTGGGRDDNRGGNGRGGYRGNRENREGGRGGERRFDRNKGGDHRGSHRGERAPGGRGRGRSERSEG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias587-634Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000021
EMBL· GenBank· DDBJ
AAW87454.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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