Q5CSM7 · Q5CSM7_CRYPI
- ProteinPyruvate kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids532 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- ATP + pyruvate = ADP + H+ + phosphoenolpyruvate
Cofactor
Pathway
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | kinase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Molecular Function | pyruvate kinase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyruvate kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Cryptosporidiidae > Cryptosporidium
Accessions
- Primary accessionQ5CSM7
Proteomes
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 32 | Interchain (with C-318) | ||||
Sequence: C | ||||||
Disulfide bond | 318 | Interchain (with C-32) | ||||
Sequence: C | ||||||
Disulfide bond | 519↔523 | |||||
Sequence: CPGSC |
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 50-381 | Pyruvate kinase barrel | ||||
Sequence: RKTQIICTIGPSCNNVESLIGLIDKGMSVARLNFSHGDHESHFKTLQNIREAAKARPHSTVGIMLDTKGPEIRTGMLEGGKPIELKAGQTLKITTDYSMLGNSECISCSYSLLPKSVQIGSTVLIADGSLSTQVLEIGDDFIVCKVLNSVTIGERKNMNLPGCKVHLPIIGDKDRHDIVDFALKYNLDFIALSFVQNGADVQLCRQIISENTQYSNGIPSSIKIISKIENLEGVINFDSICSESDGIMVARGDLGMEIPPEKIFVAQKCMISKCNVAGKPVVTATQMLESMIKSNRPTRAEMTDVANAVLDGSDCVMLSGETANGAFPFDAV | ||||||
Domain | 416-529 | Pyruvate kinase C-terminal | ||||
Sequence: EAIACSAVESAHDVNAKLIITITETGNTARLISKYRPSQTIIACTAKPEVARGLKIARGVKTYVLNSIHHSEVVISNALALAKEESLIESGDFAIAVHGVKESCPGSCNLMKIV |
Sequence similarities
Belongs to the pyruvate kinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length532
- Mass (Da)57,172
- Last updated2005-04-12 v1
- ChecksumF2950B843B61A41A
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: I |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAEE01000006 EMBL· GenBank· DDBJ | EAK88569.1 EMBL· GenBank· DDBJ | Genomic DNA |