Q5BD77 · HOGA1_EMENI

Function

function

Catalyzes the final step in the metabolic pathway of hydroxyproline (By similarity).
Involved in osmoadaptation

Catalytic activity

Activity regulation

Inhibited by divalent cations.

Features

Showing features for binding site, site, active site.

Type
IDPosition(s)Description
Binding site49-50substrate
Site144Involved in proton transfer during cleavage
Active site173Schiff-base intermediate with substrate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
  • EC number
  • Alternative names
    • Dihydrodipicolinate synthase-like (DHDPS-like protein)
    • Probable 2-keto-4-hydroxyglutarate aldolase (Probable KHG-aldolase)

Gene names

    • ORF names
      AN1503

Organism names

Accessions

  • Primary accession
    Q5BD77
  • Secondary accessions
    • C8VMN4

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003482851-309Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial

Expression

Induction

Down-regulated when grown with elevated levels of potassium chloride.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the DapA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    309
  • Mass (Da)
    32,314
  • Last updated
    2005-04-26 v1
  • Checksum
    42D3E59113B43F66
MANRPLVPGVYVPTVAFFAENEDVDVATVEKHAAYLAKSGVAGIVVQGSNGEAVHLDREERNLITSATRHALDSVGATSMPVIVGTGAPSTRETINLCKDAAAAGGDYVLVLPPSYYKSLVSSAALLDHFRAVADASPIPVLIYNFPGASAGLDLSSDDILALSSHPNIIGTKLTCGNTGKLTRIVAQAGPSFLTFGGSCDFTLQTLIGGGAGVIAGTANIIPRACVRIMELYRAGRVEEAQKVQAIVARADWLAIKGGFVAVKSALQSYRGYGQQPRRPCVAPSSEEAAALKEAFSESIELERQLESQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AACD01000023
EMBL· GenBank· DDBJ
EAA63816.1
EMBL· GenBank· DDBJ
Genomic DNA
BN001307
EMBL· GenBank· DDBJ
CBF84998.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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