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Q5BAD0 · EFM7_EMENI

Function

function

S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

Features

Showing features for binding site.

125920406080100120140160180200220240
TypeIDPosition(s)Description
Binding site53S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site80-82S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site102S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site138S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site164S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionN-terminal protein N-methyltransferase activity
Molecular Functionprotein-lysine N-methyltransferase activity
Biological ProcessN-terminal peptidyl-glycine methylation
Biological Processpeptidyl-lysine dimethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein N-terminal and lysine N-methyltransferase efm7
  • EC number
  • Alternative names
    • Elongation factor methyltransferase 7

Gene names

    • Name
      efm7
    • Synonyms
      nnt1
    • ORF names
      AN2500

Organism names

Accessions

  • Primary accession
    Q5BAD0
  • Secondary accessions
    • C8VPH9

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000968951-259Protein N-terminal and lysine N-methyltransferase efm7

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    259
  • Mass (Da)
    29,157
  • Last updated
    2017-05-10 v2
  • MD5 Checksum
    4E0B4568028A64833FE94986286A562C
MADDFDTGDMFKDPEGFYPPEKEPTFAEHRMLSGQVVRVRLVGSHPLYGNMLWNAGRISSEYIETHAPTLIAGKDVLEIGAAAGVPSIVSAIMGARTTVMTDYPDPDLVDNMRQNADASASMIPTDPPSSLHVTGYKWGSDVEPLKAYLPEESRADGFDVLIMADVVYSHREHGNLVKTMQETLKRQKDAVALVIFTPYEPWLLPQTERFFPLAEQGGFTVTKVFEKLTEKLLFENDPGDERLRRTVFGYELRWKDELR

Sequence caution

The sequence CBF86981.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence EAA63985.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AACD01000042
EMBL· GenBank· DDBJ
EAA63985.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
BN001307
EMBL· GenBank· DDBJ
CBF86981.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.

Genome annotation databases

Similar Proteins

Disclaimer

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