Q5A6P6 · QDR1_CANAL

Function

function

MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence. No substrate for transport has been identified yet, but plays an important role in the growth in the host.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane raft
Cellular Componentplasma membrane
Molecular Functiontransmembrane transporter activity
Biological Processlipid homeostasis
Biological Processmembrane raft assembly
Biological Processtransmembrane transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    MFS antiporter QDR1

Gene names

    • Name
      QDR
    • ORF names
      CaO19.508, CaO19.8138
    • Ordered locus names
      CAALFM_CR04210CA

Organism names

Accessions

  • Primary accession
    Q5A6P6
  • Secondary accessions
    • A0A1D8PSR1

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Note: Preferentially localizes to membrane rafts.

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-41Cytoplasmic
Transmembrane42-62Helical; Name=1
Topological domain63-75Extracellular
Transmembrane76-96Helical; Name=2
Topological domain97-106Cytoplasmic
Transmembrane107-129Helical; Name=3
Topological domain130-132Extracellular
Transmembrane133-155Helical; Name=4
Topological domain156-169Cytoplasmic
Transmembrane170-190Helical; Name=5
Topological domain191-197Extracellular
Transmembrane198-218Helical; Name=6
Topological domain219-278Cytoplasmic
Transmembrane279-299Helical; Name=7
Topological domain300-312Extracellular
Transmembrane313-333Helical; Name=8
Topological domain334-370Cytoplasmic
Transmembrane371-391Helical; Name=9
Topological domain392-397Extracellular
Transmembrane398-418Helical; Name=10
Topological domain419-432Cytoplasmic
Transmembrane433-453Helical; Name=11
Topological domain454-455Extracellular
Transmembrane456-476Helical; Name=12
Topological domain477-509Cytoplasmic

Keywords

Phenotypes & Variants

Disruption phenotype

Leads to defects in biofilm architecture.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004315991-509MFS antiporter QDR1

Expression

Induction

Expression is repressed by caspofungin and during chlamydospore formation. Also regulated during white-opaque switch, and by NRG1, TUP1 and HAP43.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    509
  • Mass (Da)
    55,432
  • Last updated
    2005-04-26 v1
  • Checksum
    612FFB8DA3E57073
MPGNREEFDIEKVLKSKKLEAIETSTEKKAPYTVFESTDKLLLIIVLSLVGFWSAISSPIYFPALPTLTKYFNTTPSVMNISVVAYLIFQGIAPTISSNLADTFGRRPVILGSIIVFCAVCIAISQTNVYWLLALLRCFQAAGIAPVFAISSGVAGDICTPANRGGMVGAVSGLQLAGNGIGGLVGAALISGFHTWRAIFIFLAIGGGVTFIFAFLVLAETSRRIVGNGSIRPKNVLNKAVLIYLPHFKNKITNDYSTLQPKGPFDILGPFKIFFQKEVFCTLLPSGMHFAAWTVSLTSLSTELESAKYNYSVMKVGLVYLPQGIACFIGSLIAGRCLNWYYRYRKNLYDKQMNDVPLNDRPPFNLVASRLTLTIVPLAMMVIGLSAFGWCLEYKKPIISIIISTILISFSASVMMSICTTMLVDLYPKQSGASASCVNLMRCWLAALFTGVLDKIISALGLGGTYTLLTGICLLTDLGLVYVLYTANQRFVNYVSPNQTAVNSDAEDY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP017630
EMBL· GenBank· DDBJ
AOW31159.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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