Q59E11 · Q59E11_DROME

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentsecretory granule
Cellular Componentsynapse
Cellular Componenttransport vesicle membrane
Biological Processanatomical structure morphogenesis
Biological Processdigestive tract development
Biological Processneuron development
Biological Processprotein dephosphorylation
Biological Processregulation of secretion

Keywords

  • Molecular function

Names & Taxonomy

Protein names

  • Submitted names
    • IA-2 protein tyrosine phosphatase, isoform D

Gene names

    • Name
      IA-2
    • Synonyms
      anon-WO0153538.69
      , CG11344
      , CG4355
      , Dmel\CG31795
      , ia-2
      , IA2
      , ia2
      , R-PTPX/1A2
    • ORF names
      CG31795
      , Dmel_CG31795

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q59E11

Proteomes

Organism-specific databases

Subcellular Location

Cytoplasmic vesicle, secretory vesicle membrane
; Single-pass type I membrane protein
Synapse

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane809-832Helical

Keywords

PTM/Processing

Keywords

Expression

Gene expression databases

    • FBgn0031294Expressed in adult anterior midgut class II enteroendocrine cell in adult midgut (Drosophila) and 237 other cell types or tissues
    • Q59E11baseline and differential

Interaction

Protein-protein interaction databases

Structure

3D structure databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-103Disordered
Compositional bias28-71Polar residues
Region621-672Disordered
Compositional bias640-672Basic and acidic residues
Region869-920Disordered
Compositional bias890-920Polar residues
Domain947-1208Tyrosine-protein phosphatase
Domain1126-1199Tyrosine specific protein phosphatases
Region1223-1306Disordered
Compositional bias1268-1293Basic and acidic residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,306
  • Mass (Da)
    145,650
  • Last updated
    2010-11-30 v2
  • Checksum
    82183CF322A4B7EE
MARNVQQRQQHPCTTTEEPKHQRARGTAGHQESATGECQQFWSKQRPPFDQQQQQEDQDPEQDPQQHPSTPQESVHHHRSPRQHELLHHQRKVPPTLPARGRHLISEGARRREVRGCGAGGGGLLCCSLDALSRPAKLLQFGVLLLILLLATHGDLAQAEGNVGCQFVRTLCIPHSEVCYDDNIFGKCIPTTGVDVEDIEKTPLTEDQSRVLATMLEELQGAGLGWDHPYVQCRIQGSLFSLQRQQQLPPNLCANLAPTPPEFGDPASALAYVRFTPPEPEAELDYYEQPAGPAQFYPALRKKQVRESDADDMYLNRMLQDRRRLRHDPSELEHFGKMDGHGQSTQLDAPSIMDAFLDTERQRIEREQQLAAAEQDADRRAEQNRLELYQILAASEPDPQPYQRKPAAQPNAMDQLEAIVEQQQQRELKEQQEQAKAPVYVPPEEVNESSELYFPDNFAPFKRARGRSRGGLAEEVEDEQPKRSFFRELAGEQGLVQEPPLRFRHVETEVDATPELVKRRPASFKQLDPYDVSLQQQEMAFESGLLRNSLTPLEEEAMLASNSFPRQAKSQRVYTEGGLLLMPQDEQDTDGMQADEPENVKQSLLANMLGFARHERLDVKKPGPLLGPPSLGSAELSNQLETEKAHKQKGHGNKEVLPAHIKGNDEDDAHKKKKVMKQQHSAEDHAPHTVDTEYVHVFVKNPIDSWNDGQRIMKELEQILHMQGYFSYLTVQQHEVSFRVNSNNPERKTAGDVARTINENRGVKNNIQRRVGFYVLHAGVGDVIKDLQDPSVSSSRIELAEQGPDVTHIMAYMFAGAGAAAVIVIFVTLILIKRHDRKRDKLGGLQSGIAGAETCSKDYQELCRARMAGKAGGGGNSTGGAAGGGSNEPAPSGRITSLSKENEGRPPSSRSSTSSWSEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPANTSGEKRELDKDPVVGGGSSSTTTKEPLKEDKAQEAAEEEAPTSSSKAAAAAKKEKEKDKDKEEKQAKDQAKVAEPRTPAKSAKQAKK

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9VPV8Q9VPV8_DROMEIA-21319
M9PAZ4M9PAZ4_DROMEIA-21318

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias28-71Polar residues
Compositional bias640-672Basic and acidic residues
Compositional bias890-920Polar residues
Compositional bias1268-1293Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014134
EMBL· GenBank· DDBJ
AAF51431.4
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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