Q59998 · ATZN_SYNY3
- ProteinZinc-transporting ATPase
- GeneziaA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids721 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- ATP + H2O + Zn2+(in) = ADP + H+ + phosphate + Zn2+(out)
CHEBI:30616 + CHEBI:15377 + Zn2+ (in)CHEBI:29105= CHEBI:456216 + CHEBI:15378 + CHEBI:43474 + Zn2+ (out)CHEBI:29105
Features
Showing features for binding site, active site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | cadmium ion transmembrane transporter activity | |
Molecular Function | metal ion binding | |
Molecular Function | P-type zinc transporter activity | |
Biological Process | metal ion transport | |
Biological Process | transmembrane transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameZinc-transporting ATPase
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Merismopediaceae > Synechocystis
Accessions
- Primary accessionQ59998
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-107 | Cytoplasmic | ||||
Sequence: MTQSSPLKTQQMQVGGMDCTSCKLKIEGSLERLKGVAEASVTVATGRLTVTYDPKQVSEITIQERIAALGYTLAEPKSSVTLNGHKHPHSHREEGHSHSHGAGEFNL | ||||||
Transmembrane | 108-128 | Helical | ||||
Sequence: KQELLPVLTAIALFTIAILFE | ||||||
Topological domain | 129-140 | Extracellular | ||||
Sequence: QPLHNTPGQIAE | ||||||
Transmembrane | 141-160 | Helical | ||||
Sequence: FAVIIPAYLLSGWTVLKTAG | ||||||
Topological domain | 161-167 | Cytoplasmic | ||||
Sequence: RNILRGQ | ||||||
Transmembrane | 168-187 | Helical | ||||
Sequence: IFDENFLMTIATLGALAIHQ | ||||||
Topological domain | 188-190 | Extracellular | ||||
Sequence: LPE | ||||||
Transmembrane | 191-210 | Helical | ||||
Sequence: AVAVMLFFRVGELFQEYSVG | ||||||
Topological domain | 211-344 | Cytoplasmic | ||||
Sequence: RSRRSIKALLEARPDTANLKRNGTVQQVSPETVQVDDLILVKPGEKVPLDGEILGGTSQVDTSALTGESVPGTVKPGDTILAGMINQSGVLTIRVTKLFSESSIAKVLDLVENASSKKASTEKFITQFARYYTP | ||||||
Transmembrane | 345-363 | Helical | ||||
Sequence: VIVFLSLAVALLPPLFIPG | ||||||
Topological domain | 364-369 | Extracellular | ||||
Sequence: ADRADW | ||||||
Transmembrane | 370-387 | Helical | ||||
Sequence: VYRALVLLVISCPCGLVI | ||||||
Topological domain | 388-671 | Cytoplasmic | ||||
Sequence: SIPLGYFGGIGGAAKHGILIKGSTFLDSLTAVKTVVFDKTGTLTKGTFKVTQVVTKNGFSESELLTLAAKAESHSTHPIALSIREAYAQSIADSEVADYEEIAGHGIRAVVQNQVVIAGNDRLLHREKIDHDTCDVAGTVVHLAVDGRYGGYILIADEIKEDAVQAIRDLKRMGVEKTVMLTGDSEIVAQSVAQQIGLDAFVAELLPEEKVDEIEQLLDPSGKAKLAFVGDGINDAPVIARADVGIAMGGLGSDAAIETADVVLMTDAPSKVAEAIHVARKTRQ | ||||||
Transmembrane | 672-693 | Helical | ||||
Sequence: IVVQNIVLALGIKALFIALGTI | ||||||
Topological domain | 694-701 | Extracellular | ||||
Sequence: GLATLWEA | ||||||
Transmembrane | 702-717 | Helical | ||||
Sequence: VFADVGVALLAILNAT | ||||||
Topological domain | 718-721 | Cytoplasmic | ||||
Sequence: RIAK |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000046333 | 1-721 | Zinc-transporting ATPase | |||
Sequence: MTQSSPLKTQQMQVGGMDCTSCKLKIEGSLERLKGVAEASVTVATGRLTVTYDPKQVSEITIQERIAALGYTLAEPKSSVTLNGHKHPHSHREEGHSHSHGAGEFNLKQELLPVLTAIALFTIAILFEQPLHNTPGQIAEFAVIIPAYLLSGWTVLKTAGRNILRGQIFDENFLMTIATLGALAIHQLPEAVAVMLFFRVGELFQEYSVGRSRRSIKALLEARPDTANLKRNGTVQQVSPETVQVDDLILVKPGEKVPLDGEILGGTSQVDTSALTGESVPGTVKPGDTILAGMINQSGVLTIRVTKLFSESSIAKVLDLVENASSKKASTEKFITQFARYYTPVIVFLSLAVALLPPLFIPGADRADWVYRALVLLVISCPCGLVISIPLGYFGGIGGAAKHGILIKGSTFLDSLTAVKTVVFDKTGTLTKGTFKVTQVVTKNGFSESELLTLAAKAESHSTHPIALSIREAYAQSIADSEVADYEEIAGHGIRAVVQNQVVIAGNDRLLHREKIDHDTCDVAGTVVHLAVDGRYGGYILIADEIKEDAVQAIRDLKRMGVEKTVMLTGDSEIVAQSVAQQIGLDAFVAELLPEEKVDEIEQLLDPSGKAKLAFVGDGINDAPVIARADVGIAMGGLGSDAAIETADVVLMTDAPSKVAEAIHVARKTRQIVVQNIVLALGIKALFIALGTIGLATLWEAVFADVGVALLAILNATRIAK |
Keywords
- PTM
Proteomic databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 8-74 | HMA | ||||
Sequence: KTQQMQVGGMDCTSCKLKIEGSLERLKGVAEASVTVATGRLTVTYDPKQVSEITIQERIAALGYTLA | ||||||
Region | 80-101 | Disordered | ||||
Sequence: VTLNGHKHPHSHREEGHSHSHG | ||||||
Compositional bias | 86-101 | Basic and acidic residues | ||||
Sequence: KHPHSHREEGHSHSHG |
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length721
- Mass (Da)76,884
- Last updated1996-11-01 v1
- ChecksumBE187EB3900EC58B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 86-101 | Basic and acidic residues | ||||
Sequence: KHPHSHREEGHSHSHG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000022 EMBL· GenBank· DDBJ | BAA10707.1 EMBL· GenBank· DDBJ | Genomic DNA |