Q59738 · BFR_RHOCA

Function

function

Iron-storage protein, whose ferroxidase center binds Fe2+, oxidizes it using dioxygen to Fe3+, and participates in the subsequent Fe3+ oxide mineral core formation within the central cavity of the BFR protein shell.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site18Fe cation 1 (UniProtKB | ChEBI)
Binding site51Fe cation 1 (UniProtKB | ChEBI)
Binding site51Fe cation 2 (UniProtKB | ChEBI)
Binding site52Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); ligand shared between dimeric partners; axial binding residue
Binding site54Fe cation 1 (UniProtKB | ChEBI)
Binding site94Fe cation 2 (UniProtKB | ChEBI)
Binding site127Fe cation 1 (UniProtKB | ChEBI)
Binding site127Fe cation 2 (UniProtKB | ChEBI)
Binding site130Fe cation 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionferric iron binding
Molecular Functionferrous iron transmembrane transporter activity
Molecular Functionferroxidase activity
Molecular Functionheme binding
Biological Processintracellular sequestering of iron ion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      bfr

Organism names

Accessions

  • Primary accession
    Q59738

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001926111-161Bacterioferritin

Interaction

Subunit

Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-145Ferritin-like diiron

Sequence similarities

Belongs to the bacterioferritin family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    161
  • Mass (Da)
    18,173
  • Last updated
    1997-11-01 v1
  • Checksum
    9E534CBC531EC709
MKGDAKVIEFLNAALRSELTAISQYWVHFRLQEDWGLAKMAKKSREESIEEMGHADKIIARILFLEGHPNLQKLDPLRIGEGPRETLECDLAGEHDALKLYREARDYCAEVGDIVSKNIFESLITDEEGHVDFLETQISLYDRLGPQGFALLNAAPMDAAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z54247
EMBL· GenBank· DDBJ
CAA91017.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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