Q59288 · CSLA_PEDHD

Function

Catalytic activity

  • Eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.
    EC:4.2.2.5 (UniProtKB | ENZYME | Rhea)

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )
Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for active site, binding site.

170050100150200250300350400450500550600650700
TypeIDPosition(s)Description
Active site225
Active site234
Active site288
Binding site405Ca2+ (UniProtKB | ChEBI)
Binding site407Ca2+ (UniProtKB | ChEBI)
Binding site416Ca2+ (UniProtKB | ChEBI)
Binding site417Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functioncarbohydrate binding
Molecular Functionchondroitin AC lyase activity
Molecular Functionmetal ion binding
Biological Processcarbohydrate metabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

    • PL8Polysaccharide Lyase Family 8

Names & Taxonomy

Protein names

  • Recommended name
    Chondroitinase-AC
  • EC number
  • Alternative names
    • Chondroitin sulfate AC lyase
    • Chondroitin-AC eliminase
    • Chondroitin-AC lyase

Gene names

    • Name
      cslA
    • Synonyms
      chnAC
    • Ordered locus names
      Phep_0786

Organism names

Accessions

  • Primary accession
    Q59288
  • Secondary accessions
    • C6Y215

Proteomes

Subcellular Location

Phenotypes & Variants

Chemistry

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_000002492723-700Chondroitinase-AC
Glycosylation328O-linked (Man...) serine
Glycosylation455O-linked (Man...) serine

Keywords

PTM databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the polysaccharide lyase 8 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    700
  • Mass (Da)
    79,694
  • Last updated
    1996-11-01 v1
  • Checksum
    C36B608FCAFFC656
MKKLFVTCIVFFSILSPALLIAQQTGTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVELK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U27583
EMBL· GenBank· DDBJ
AAC83383.1
EMBL· GenBank· DDBJ
Genomic DNA
CP001681
EMBL· GenBank· DDBJ
ACU03008.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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