Q59282 · ARGD_CORGL
- ProteinAcetylornithine aminotransferase
- GeneargD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids391 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Miscellaneous
May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.
Catalytic activity
- N2-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate
Cofactor
Note: Binds 1 pyridoxal phosphate per subunit.
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 4/4.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 110-111 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 136 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 139 | N2-acetyl-L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 224-227 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 281 | N2-acetyl-L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 282 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | identical protein binding | |
Molecular Function | N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | arginine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetylornithine aminotransferase
- EC number
- Short namesACOAT
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionQ59282
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000112741 | 1-391 | Acetylornithine aminotransferase | ||
Modified residue | 253 | N6-(pyridoxal phosphate)lysine | |||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length391
- Mass (Da)41,206
- Last updated2002-07-11 v2
- MD5 Checksum3883A2E23E12CA77418F043A345F08C2
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 267-268 | in Ref. 1; CAA60099 and 2; AAC24815 | |||
Sequence conflict | 312-313 | in Ref. 1; CAA60099 and 2; AAC24815 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X86157 EMBL· GenBank· DDBJ | CAA60099.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF049897 EMBL· GenBank· DDBJ | AAC24815.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BA000036 EMBL· GenBank· DDBJ | BAB98790.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BX927152 EMBL· GenBank· DDBJ | CAF21408.1 EMBL· GenBank· DDBJ | Genomic DNA |