Q58EV5 · Q58EV5_MOUSE

  • Protein
    High mobility group protein B1
  • Gene
    Hmgb1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Features

Showing features for dna binding.

121520406080100120140160180200
TypeIDPosition(s)Description
DNA binding9-79HMG box
DNA binding95-163HMG box

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome
Cellular Componentendoplasmic reticulum-Golgi intermediate compartment
Cellular Componentnucleus
Cellular Componentplasma membrane
Molecular Functionbubble DNA binding
Molecular FunctionDNA binding, bending
Molecular Functionfour-way junction DNA binding
Molecular Functionsupercoiled DNA binding
Biological Processautophagy
Biological Processchemotaxis
Biological ProcessDNA geometric change
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological Processinnate immune response
Biological Processregulation of transcription by RNA polymerase II

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    High mobility group protein B1
  • Alternative names
    • High mobility group protein 1

Gene names

    • Name
      Hmgb1

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • C57BL/6J
    • Czech II
    • FVB/N
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q58EV5

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain9-79HMG box
Compositional bias76-94Basic and acidic residues
Region76-95Disordered
Domain95-163HMG box
Compositional bias161-187Basic and acidic residues
Region161-215Disordered
Compositional bias188-215Acidic residues

Sequence similarities

Belongs to the HMGB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    215
  • Mass (Da)
    24,894
  • Last updated
    2005-05-10 v1
  • Checksum
    8A868DE266D552B5
MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias76-94Basic and acidic residues
Compositional bias161-187Basic and acidic residues
Compositional bias188-215Acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC091741
EMBL· GenBank· DDBJ
AAH91741.1
EMBL· GenBank· DDBJ
mRNA
BC094030
EMBL· GenBank· DDBJ
AAH94030.1
EMBL· GenBank· DDBJ
mRNA
BC110667
EMBL· GenBank· DDBJ
AAI10668.1
EMBL· GenBank· DDBJ
mRNA
BC111468
EMBL· GenBank· DDBJ
AAI11469.1
EMBL· GenBank· DDBJ
mRNA
AK037928
EMBL· GenBank· DDBJ
BAC29902.1
EMBL· GenBank· DDBJ
mRNA
AK084841
EMBL· GenBank· DDBJ
BAC39289.1
EMBL· GenBank· DDBJ
mRNA
AK157846
EMBL· GenBank· DDBJ
BAE34226.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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